Evidence map›Paper›PMID 40142400›Full record

ReviewMicroorganisms2025

A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals.

Akikazu Sakudo, Koichi Furusaki, Rumiko Onishi, Takashi Onodera, Yasuhiro Yoshikawa

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akikazu SakudoSchool of Veterinary Medicine, Okayama University of Science, Imabari 794-8555, Ehime, Japan.
Koichi FurusakiMineral Activation Technical Research Center, Omuta 836-0041, Fukuoka, Japan.
Rumiko OnishiSanta Mineral Co., Ltd., Minato-ku 105-0013, Tokyo, Japan.
Takashi OnoderaEnvironmental Science for Sustainable Development, The University of Tokyo, Bunkyo-ku 113-8657, Tokyo, Japan.
Yasuhiro YoshikawaSchool of Veterinary Medicine, Okayama University of Science, Imabari 794-8555, Ehime, Japan.

Funding

Japan Society for the Promotion of Science 20K03919Japan Society for the Promotion of Science 24K07444
6 · The paper itself

Abstract

Recent studies on utilizing biological functions of natural substances that mimic the mesoscopic structures (nanoparticles of about 50 to 500 nm) found in plant growth points and coral skeletons have been reported. After the calcium hydrogen carbonate contained in materials derived from plants and coral are separated, the crystals of the mesoscopic structure can be reformed by applying a high voltage under a specific set of conditions. A suspension of these mesoscopic crystals in water (CAC-717) can be used as an effective disinfectant. CAC-717 exhibits universal virucidal activity against both enveloped and non-enveloped viruses as well as bactericidal and anti-prion activity. Moreover, in comparison to sodium hypochlorite, the potency of CAC-717 as a disinfectant is less susceptible to organic substances such as albumin. The disinfection activity of CAC-717 is maintained for at least 6 years and 4 months after storage at room temperature. CAC-717 is non-irritating and harmless to humans and animals, making it a promising biosafe disinfectant. This review explores the disinfection activity of CAC-717 as well as the potential and future uses of this material.

Indexed as

Ca(HCO3)2disinfectantsdisinfectioninactivationnanotechnologyprion

Identifiers

PMID40142400
PMCPMC11946018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.