Evidence map›Paper›PMID 40142379›Full record

ArticleMicroorganisms2025

Virus Infection of a Freshwater Cyanobacterium Contributes Significantly to the Release of Toxins Through Cell Lysis.

Victoria Lee, Isaac Meza-Padilla, Jozef I Nissimov

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Victoria LeeDepartment of Biology, University of Waterloo, 200 University Ave. West, Waterloo, ON N2L 3G1, Canada.
Isaac Meza-PadillaDepartment of Biology, University of Waterloo, 200 University Ave. West, Waterloo, ON N2L 3G1, Canada.
Jozef I NissimovDepartment of Biology, University of Waterloo, 200 University Ave. West, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0002-2220-6136

Funding

Natural Sciences and Engineering Research Council 2022-00329Natural Sciences and Engineering Research Council 2022-03350
6 · The paper itself

Abstract

Toxic algal-bloom-forming cyanobacteria are a persistent problem globally for many aquatic environments. Their occurrence is attributed to eutrophication and rising temperatures due to climate change. The result of these blooms is often the loss of biodiversity, economic impacts on tourism and fisheries, and risks to human and animal health. Of emerging interest is the poorly understood interplay between viruses and toxic species that form blooms. This is because recent studies have suggested that viruses may exacerbate the harmful effects of these blooms by contributing to the release of toxins into a dissolved phase upon cell lysis. However, to date, there is no experimental evidence that explicitly implicates viruses in microcystin release. Here, we show experimentally that a virus infection of the toxin-producing, harmful, algal-bloom-forming cyanobacterium

Indexed as

cyanophageharmful algal bloommicrocystinMicrocystis aeruginosavirus infection

Identifiers

PMID40142379
PMCPMC11944701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.