Evidence map›Paper›PMID 40142301›Full record

ArticleMedicina (Kaunas, Lithuania)2025

Efficacy and Clinical Outcomes of Crizotinib in Patients with ROS1-Rearranged NSCLC: A Multicenter Study.

Alper Topal, Goncagul Akdag, Sedat Yildirim, Oguzcan Kinikoglu, Deniz Isik, Gizem Yildirim, Salih Tunbekici, Fatih Kus, Aydın Acarbay, Murad Guliyev and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alper TopalDepartment of Medical Oncology, Health Science University, Gulhane Research and Training Hospital, Ankara 06010, Turkey.ORCID 0000-0002-9679-9245
Goncagul AkdagDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0002-6221-0623
Sedat YildirimDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0002-2423-6902
Oguzcan KinikogluDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0001-5983-3291
Deniz IsikDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0003-4398-5148
Gizem YildirimDepartment of Medical Oncology, Health Science University, Gulhane Research and Training Hospital, Ankara 06010, Turkey.
Salih TunbekiciDivision of Medical Oncology, Departmant of Internal Medicine, Ege Universitiy, Izmir 35100, Turkey.
Fatih KusDepartment of Medical Oncology, Hacettepe University Oncology Institue, Ankara 06230, Turkey.ORCID 0000-0003-1650-154X
Aydın AcarbayDivision of Medical Oncology, Departmant of Internal Medicine, Istanbul Medeniyet University, Istanbul 34730, Turkey.
Murad GuliyevDivision of Medical Oncology, Departmant of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.ORCID 0000-0002-2981-8098
Nargiz MajidovaDepartment of Medical Oncology, Marmara University Pendik Training and Research Hospital, Istanbul 34854, Turkey.ORCID 0000-0002-2575-5819
Yasin KutluDepartment of Medical Oncology, Tokat State Hospital, Tokat 60000, Turkey.ORCID 0000-0003-2184-634X
Mustafa ErmanDepartment of Medical Oncology, Hacettepe University Oncology Institue, Ankara 06230, Turkey.ORCID 0000-0001-5884-4669
Hatice OdabasDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0002-5757-4705
Nedim TuranDepartment of Medical Oncology, Kartal Dr. Lütfi Kirdar City Hospital, Health Science University, Istanbul 34865, Turkey.ORCID 0000-0002-1140-8779
Nuri KaradurmusDepartment of Medical Oncology, Health Science University, Gulhane Research and Training Hospital, Ankara 06010, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Non-Small-Cell LungCrizotinibLung NeoplasmsProtein-Tyrosine KinasesProto-Oncogene ProteinsAdultAgedAged, 80 and overAntineoplastic AgentsFemaleGene RearrangementHumansMaleMiddle AgedProtein Kinase InhibitorsRetrospective StudiesAntineoplastic AgentsCrizotinibProtein Kinase InhibitorsProtein-Tyrosine KinasesProto-Oncogene ProteinsROS1 protein, humancrizotiniblung cancerROS1

Identifiers

PMID40142301
PMCPMC11943710

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.