Evidence map›Paper›PMID 40142244›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Enhancing Ophthalmic Diagnosis and Treatment with Artificial Intelligence.

David B Olawade, Kusal Weerasinghe, Mathugamage Don Dasun Eranga Mathugamage, Aderonke Odetayo, Nicholas Aderinto, Jennifer Teke, Stergios Boussios

Registry-linked trialAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07096232 (Orchestrated Multi Agent Artificial Intelligence), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07096232 enrolling by invitationnot on this map

Orchestrated Multi Agent Artificial Intelligence (AI) Versus Consultant Ophthalmologist: Workflow Performance in Refractive Surgery and Keratoconus Diagnosis. Demonstrating Increased Diagnostic Accuracy (Automated Evaluation for Your Eye, AEYE).

Typeobservational_patient_registrySponsorHazem Yassin ClinicsRan2025 to 2025Enrolled50ConditionsKeratoconus, Refractive Surgery, Machine Learning, Artifical IntelligenceArmsMulti-Agent AI Diagnostic Workflow (AEYE)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Human Crystallin Variation and Cataract.Investigative ophthalmology & visual science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David B OlawadeDepartment of Allied and Public Health, School of Health, Sport and Bioscience, University of East London, London E16 2RD, UK.ORCID 0000-0003-0188-9836
Kusal WeerasingheDepartment of Research and Innovation, Medway NHS Foundation Trust, Gillingham ME7 5NY, UK.
Mathugamage Don Dasun Eranga MathugamageNational Eye Hospital, Colombo 01000, Sri Lanka.
Aderonke OdetayoSchool of Nursing, Tung Wah College, Hong Kong SAR, China.ORCID 0000-0001-8509-0460
Nicholas AderintoDepartment of Medicine and Surgery, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.
Jennifer TekeDepartment of Research and Innovation, Medway NHS Foundation Trust, Gillingham ME7 5NY, UK.
Stergios BoussiosDepartment of Research and Innovation, Medway NHS Foundation Trust, Gillingham ME7 5NY, UK.ORCID 0000-0002-2512-6131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of artificial intelligence (AI) in ophthalmology is transforming the field, offering new opportunities to enhance diagnostic accuracy, personalize treatment plans, and improve service delivery. This review provides a comprehensive overview of the current applications and future potential of AI in ophthalmology. AI algorithms, particularly those utilizing machine learning (ML) and deep learning (DL), have demonstrated remarkable success in diagnosing conditions such as diabetic retinopathy (DR), age-related macular degeneration, and glaucoma with precision comparable to, or exceeding, human experts. Furthermore, AI is being utilized to develop personalized treatment plans by analyzing large datasets to predict individual responses to therapies, thus optimizing patient outcomes and reducing healthcare costs. In surgical applications, AI-driven tools are enhancing the precision of procedures like cataract surgery, contributing to better recovery times and reduced complications. Additionally, AI-powered teleophthalmology services are expanding access to eye care in underserved and remote areas, addressing global disparities in healthcare availability. Despite these advancements, challenges remain, particularly concerning data privacy, security, and algorithmic bias. Ensuring robust data governance and ethical practices is crucial for the continued success of AI integration in ophthalmology. In conclusion, future research should focus on developing sophisticated AI models capable of handling multimodal data, including genetic information and patient histories, to provide deeper insights into disease mechanisms and treatment responses. Also, collaborative efforts among governments, non-governmental organizations (NGOs), and technology companies are essential to deploy AI solutions effectively, especially in low-resource settings.

Indexed as

Artificial IntelligenceEye DiseasesOphthalmologyDeep LearningHumansage-related macular degenerationartificial intelligencediabetic retinopathyglaucomamachine learningophthalmology

Identifiers

PMID40142244
PMCPMC11943519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.