Evidence map›Paper›PMID 40142112›Full record

ArticleMolecules (Basel, Switzerland)2025

Synthesis of β-Cyclodextrin-Functionalized Silver Nanoparticles and Their Application for Loading Cytisine and Its Phosphorus Derivative.

Serik D Fazylov, Oralgazy A Nurkenov, Zhangeldy S Nurmaganbetov, Akmaral Zh Sarsenbekova, Ryszhan Ye Bakirova, Olzhas T Seilkhanov, Alexandr K Sviderskiy, Ardak K Syzdykov, Anel Zh Mendibayeva

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serik D FazylovInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0002-4240-6450
Oralgazy A NurkenovInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0003-1878-2787
Zhangeldy S NurmaganbetovInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0002-0978-5663
Akmaral Zh SarsenbekovaDepartment of Physical and Analytical Chemistry, Karaganda University of the Name of E.A. Buketov, Karaganda 100074, Kazakhstan.ORCID 0000-0002-8951-3616
Ryszhan Ye BakirovaDepartment of Internal Diseases, Karaganda Medical University, Karaganda 100012, Kazakhstan.ORCID 0000-0002-1592-8579
Olzhas T SeilkhanovLaboratory of Engineering Profile NMR-Spectroscopy, Sh. Ualikhanov Kokshetau University, Kokshetau 120000, Kazakhstan.ORCID 0000-0002-2322-8863
Alexandr K SviderskiyDepartment of Mining, Metallurgy and Natural Sciences, Zhezkazgan University of the Name of O. Baikonurov, Zhezkazgan 100600, Kazakhstan.ORCID 0000-0001-7277-5882
Ardak K SyzdykovInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0009-0008-9124-7821
Anel Zh MendibayevaInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0001-6123-3340

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan BR24992921
6 · The paper itself

Abstract

In this study, the synthesis and properties of β-cyclodextrin-functionalized silver nanoparticles and their loading with a drug component are considered. β-Cyclodextrin was used as a reducing agent and stabilizer in the preparation of silver nanoparticles. The use of β-CD-AgNPs in loading molecules of the alkaloid cytisine (Cz) and its O,O-dimethyl-N-cytisinilphosphate (CzP) derivative, which have pronounced antiviral properties, was studied. The formation of β-CD-Cz-AgNPs and β-CD-CzP-AgNPs was confirmed by UV spectroscopy and X-ray diffraction spectroscopy. Scanning electron microscopy and transmission electron microscopy showed that the obtained β-CD-Cz-AgNP and β-CD-CzP-AgNP nanocomposites were well dispersed with particle sizes in the range of 3-20 nm.

Indexed as

antiviral activitycytisineencapsulationinclusion complexnanocompositessilver nanoparticlesthermal decompositionβ-cyclodextrin

Identifiers

PMID40142112
PMCPMC11944286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.