Evidence map›Paper›PMID 40141891›Full record

ArticleMicromachines2025

An Electrochemical Immunosensor for Sensitive Detection of Exosomes Based on Au/MXenes and AuPtPdCu.

Jie Gao, Rong Yang, Xiaorui Zhu, Jiling Shi, Sufei Wang, Aihua Jing

Abstract read
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie GaoSchool of Secondary Vocational Education, The Open University of China, Beijing 100031, China.
Rong YangSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Xiaorui ZhuCollaboration Innovative Center of Henan Province for Energy-Saving Building Materials, Xinyang Normal University, Xinyang 464000, China.
Jiling ShiSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Sufei WangSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Aihua JingSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are important biomarkers for liquid biopsy in early cancer screening which play important roles in many biological processes, including apoptosis, inflammatory response, and tumor metastasis. In this study, an electrochemical aptamer immunosensor based on Au/MXene and AuPtPdCu was constructed for the sensitive detection of colorectal cancer-derived exosomes. AuNPs were deposited in situ on the surface of MXenes as a sensing platform due to their large specific area, excellent conductivity, and higher number of active sites for aptamer immobilization. The aptamer CD63 immobilized on Au/MXene can specifically capture target exosomes. Therefore, the AuPtPdCu-Apt nanoprobe further enhanced the sensitivity and accuracy of the immunosensor. A low limit of detection of 19 particles μL

Indexed as

AuPtPdCuearly diagnosiselectrochemical biosensorexosome detectionmulti-metallic nanoparticlesMXenes

Identifiers

PMID40141891
PMCPMC11944654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.