ReviewMicromachines2025
Mechanical Stimulation of Red Blood Cells Aging: Focusing on the Microfluidics Application.
Review in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- A Microfluidic Method for Simultaneous Assessment of Blood Viscosity and Red Blood Cell Aggregation During Continuous Syringe Delivery.Sensors (Basel, Switzerland) · 2026Article
- Blood Mechanical Intelligence: From Force Sensing to Precision Mechanomedicine.Research (Washington, D.C.) · 2026Review
- Redefining the concept of erythrocyte senescence: is eryptosis fundamentally different from erythrocyte senescence.GeroScience · 2025Review
- Article
- Numerical simulation of red blood cells migration and platelets margination for blood flow in micro-vessels with fusiform aneurysms.Scientific reports · 2025Article
- The interactions of non-functionalized polystyrene nanoparticles with human albumin and erythrocyte proteins: implications and potential consequences.Scientific reports · 2025Article
- The Mechanical Properties of Erythrocytes Are Influenced by the Conformational State of Albumin.Cells · 2025Review
- Microfluidic Chip for Quantitatively Assessing Hemorheological Parameters.Micromachines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human red blood cells (RBCs) are highly differentiated cells, essential in almost all physiological processes. During their circulation in the bloodstream, RBCs are exposed to varying levels of shear stress ranging from 0.1-10 Pa under physiological conditions to 50 Pa in arterial stenotic lesions. Moreover, the flow of blood through splenic red pulp and through artificial organs is associated with brief exposure to even higher levels of shear stress, reaching up to hundreds of Pa. As a result of this exposure, some properties of the cytosol, the cytoskeleton, and the cell membrane may be significantly affected. In this review, we aim to systematize the available information on RBC response to shear stress by focusing on reported changes in various red cell properties. We pay special attention to the results obtained using microfluidics, since these devices allow the researcher to accurately simulate blood flow conditions in the capillaries and spleen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.