Evidence map›Paper›PMID 40141847›Full record

ReviewLife (Basel, Switzerland)2025

Efficacy of Neurorehabilitation Approaches in Traumatic Brain Injury Patients: A Comprehensive Review.

Diana Andrei, Alexandra Laura Mederle, Laura Andreea Ghenciu, Claudia Borza, Alexandra Corina Faur

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diana AndreiDepartment XVI, Discipline of Medical Rehabilitation, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.ORCID 0000-0001-6019-9734
Alexandra Laura MederleDepartment XIV, Discipline of Dermatology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Laura Andreea GhenciuDepartment III, Discipline of Pathophysiology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-5326-5438
Claudia BorzaDepartment III, Discipline of Pathophysiology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Alexandra Corina FaurDepartment I, Disciplone of Anatomy and Embriology, 'Victor Babes' University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI) represents a significant public health issue, causing long-term disabilities and imposing considerable socioeconomic and healthcare challenges. While advancements in acute care have improved survival rates, the demand for effective neurorehabilitation is increasing. This narrative review explores the evidence on neurorehabilitation strategies for TBI, focusing on interventions targeting cognitive, motor, and psychological recovery. A total of 32 studies were included and categorized into six approaches: non-invasive brain stimulation, virtual reality (VR), computer-based training, telerehabilitation, robot-assisted therapy (RAT), and mixed approaches. Non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), showed variable effectiveness in improving cognitive outcomes. VR-based therapies enhanced attention and executive functions, while RAT, such as Lokomat and exoskeletons, improved gait symmetry and functional mobility. Computer-assisted programs demonstrated benefits in rehabilitating social cognition and executive functions. Telerehabilitation and telephone-based treatments provided short-term gains but lacked sustained effects. Overall, cognitive improvements were better described and represented, while several motor improvements lacked consistency. Despite the promising results, significant gaps remain, including heterogeneity in methodologies, small sample sizes, and limited long-term outcome data.

Indexed as

cognitive rehabilitationmotor rehabilitationneurorehabilitationnon-invasive brain stimulationrobotic deviceTBItelemonitoringtraumatic brain injuryvirtual realityVR

Identifiers

PMID40141847
PMCPMC11944267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.