Evidence map›Paper›PMID 40141846›Full record

ArticleLife (Basel, Switzerland)2025

Genetic and Epigenetic Changes in

Andres Lopez Virgen, Narendra Singh Yadav, Boseon Byeon, Yaroslav Ilnytskyy, Igor Kovalchuk

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andres Lopez VirgenDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.ORCID 0009-0000-5841-0254
Narendra Singh YadavDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.ORCID 0000-0003-0122-173X
Boseon ByeonBiomedical and Health Informatics, Computer Science Department, State University of New York, 2 S Clinton St, Syracuse, NY 13202, USA.
Yaroslav IlnytskyyDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.
Igor KovalchukDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.ORCID 0000-0002-8137-6928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous exposure to stress contributes to species diversity and drives microevolutionary processes. It is still unclear, however, whether epigenetic changes, in the form of epimutations such as, for example, differential DNA methylation, are the pre-requisite to speciation events. We hypothesized that continuous stress exposure would increase epigenetic diversity to a higher extent than genetic diversity. In this work, we have analyzed the effect of 25 consecutive generations of UV-C-stress exposure on the

Indexed as

Arabidopsis thalianadifferentially methylated cytosinesdifferentially methylated regionsepigenetic variationsgenetic variationsINDELsintergenerational inheritancemultigenerational UV-C stressphenotypic resilienceSNPsstress memorytransgenerational inheritance

Identifiers

PMID40141846
PMCPMC11943796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.