Evidence map›Paper›PMID 40141838›Full record

ArticleLife (Basel, Switzerland)2025

Predictive Factors of Non-Elevation of Carcinoembryonic Antigen 125 in Acute Heart Failure.

Raquel López-Vilella, Francisco González-Vílchez, Borja Guerrero Cervera, Víctor Donoso Trenado, Zoser Saura Carretero, Julia Martínez-Solé, Sara Huélamo Montoro, Luis Martínez Dolz, Luis Almenar Bonet

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raquel López-VilellaCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0002-9696-2313
Francisco González-VílchezCardiology Department, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.
Borja Guerrero CerveraCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0003-3359-8857
Víctor Donoso TrenadoCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0002-3105-9529
Zoser Saura CarreteroCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0009-0000-7264-8840
Julia Martínez-SoléCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0001-8084-3531
Sara Huélamo MontoroCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0009-0002-6345-3819
Luis Martínez DolzCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0001-5145-8191
Luis Almenar BonetCardiology Department, Hospital Universitari i Politècnic La Fe, Fernando Abril Martorell Avenue 106, 46026 Valencia, Spain.ORCID 0000-0002-7710-361X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to analyze the factors associated with the lack of carbohydrate antigen 125 (CA-125) elevation in cases of acute heart failure (HF) decompensation. This retrospective study was conducted on 3167 consecutive patients admitted for acute HF in the cardiology department of a referral hospital (June 2019 to June 2024). Admissions from outpatient clinics (n: 1018) and transfers from other hospitals (n: 752) were excluded. The variables of interest included clinical, echocardiographic, therapeutic, and analytical factors. Low CA-125 levels were defined as values ≤ 50 U/mL. A total of 1397 patients were included, of whom 515 had normal CA-125 levels and 882 had elevated levels. Clinically, independent predictors of low CA-125 were sinus rhythm on electrocardiogram (OR: 1.42, 95% CI: 1.12-1.64;

Indexed as

acute heart failurecarbohydrate antigen 125 (CA-125)low CA-125prognosis

Identifiers

PMID40141838
PMCPMC11944017

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.