Evidence map›Paper›PMID 40141805›Full record

ArticleLife (Basel, Switzerland)2025

Outcomes of Surgical Versus Conservative Management in Stanford Type a Aortic Dissection: A Single-Center Retrospective Study.

Irina-Anca Eremia, Mihnea-Ioan-Gabriel Popa, Cătălin-Alexandru Anghel, Teodora-Adriana Stroe, Eduard-Alexandru Eremia, Andreea Nicoleta Marinescu, Remus Iulian Nica, Silvia Nica

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irina-Anca EremiaDepartment of Family Medicine III, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-2772-8945
Mihnea-Ioan-Gabriel PopaDepartment of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-0409-7220
Cătălin-Alexandru AnghelEmergency Department, Emergency University Hospital Bucharest, 050098 Bucharest, Romania.ORCID 0009-0009-7566-7137
Teodora-Adriana StroeFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0002-8742-5628
Eduard-Alexandru EremiaFaculty of Medicine, Ludwig Maximilian University of Munich, 80336 Munich, Germany.ORCID 0009-0007-7748-2334
Andreea Nicoleta MarinescuDepartment of Radiology and Medical Imaging, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0005-3669-9030
Remus Iulian NicaDiscipline of General Surgery, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-3722-6877
Silvia NicaDepartment of Emergency and First Aid, Emergency University Hospital Bucharest, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-4491-0298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute aortic dissection (AAD) is a critical cardiovascular emergency marked by the rupture of the aortic intima, resulting in blood infiltration into the media and the formation of a false lumen. AAD incidence varies by area, emphasizing the need for better diagnostics and epidemiological investigations. Bucharest University Emergency Hospital's Emergency Department conducted this retrospective cohort analysis from May 2021 to May 2023. We examined 26 Stanford Type A aortic dissection patients to establish in-hospital mortality and one-year survival rates. The primary objective was to analyze demographic, clinical, and paraclinical factors and their impact on patient outcomes. A total of 57.7% of the study group was male and had a mean age of 58.2 years, and 69.2% of patients had hypertension, indicating its importance as a risk factor. Acute chest discomfort was reported by 53.8%, neurological problems by 30.8%, and syncope or hypotension by 42.3%. CT angiography and transthoracic echocardiogram (TTE) confirmed the diagnosis and assessed dissection severity. Pericardial effusion (19.2%) and moderate to severe aortic regurgitation (26.9%) were notable. Management varied by dissection intensity and location. Emergency surgery was performed in 61.5% of patients within 24 h of diagnosis, resulting in a 12.5% in-hospital death rate. Conservatively managed patients had a 60.0% in-hospital death rate. Timely intervention is crucial, since the surgical cohort had an 87.5% one-year survival rate compared to 30% for the conservatively managed cohort. Acute renal damage (25%), protracted mechanical ventilation (31.3%), and advanced supportive care infections were postoperative sequelae. Conservative care exacerbated visceral ischemia (20%) and heart failure (10%). Advanced age and hypotension upon admission were independent mortality predictors, emphasizing the need for early risk assessment and personalized treatment. Multimodal imaging, timely surgical referral, and excellent postoperative care improve AAD outcomes, according to this study.

Indexed as

acute aortic dissectionin-hospital mortalitypostoperative complicationsStanford Type Asurgical management

Identifiers

PMID40141805
PMCPMC11943683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.