Evidence map›Paper›PMID 40141746›Full record

ArticleLife (Basel, Switzerland)2025

Relationship Between 8-iso-prostaglandin-F

Giulio Geraci, Alessandra Sorce, Luca Zanoli, Giuseppe Cuttone, Vincenzo Calabrese, Francesco Pallotti, Valentina Paternò, Pietro Ferrara, Ligia J Dominguez, Riccardo Polosa and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Circulating GPER-1, 8-Iso-Prostaglandin FJournal of clinical medicine · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giulio GeraciDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0003-3806-1151
Alessandra SorceUnit of Nephrology and Dialysis, Hypertension Excellence Centre, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.
Luca ZanoliNephrology, Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-1678-3778
Giuseppe CuttoneDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0009-0005-5271-1810
Vincenzo CalabreseDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0001-6333-5009
Francesco PallottiDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0001-6042-6474
Valentina PaternòOperative Unit of Diabetology, Umberto I Hospital, Provincial Health Authority (ASP) of Enna, 94100 Enna, Italy.
Pietro FerraraCenter for Public Health Research, University of Milan-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-0349-3221
Ligia J DominguezDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0003-1466-8610
Riccardo PolosaDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0002-8450-5721
Jacob GeorgeCardiovascular Medicine and Therapeutics, University of Dundee Medical School, Ninewells Hospital, Dundee DD1 9SY, UK.ORCID 0000-0001-8154-8278
Giuseppe MulèUnit of Nephrology and Dialysis, Hypertension Excellence Centre, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.
Caterina CarolloUnit of Nephrology and Dialysis, Hypertension Excellence Centre, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-6767-8823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background8-iso-prostaglandin-F MATERIALS AND

methodsA total of 432 individuals aged 40-75 years were enrolled. Plasma 8-iso-PGF

resultsIndividuals with higher CV risk had significantly greater 8-iso-PGF

conclusionsThese findings highlight the potential utility of 8-iso-PGF

Indexed as

8-iso-prostaglandin-F2α cardiovascular riskchronic kidney diseasehypertensioninflammationoxidative stresspreventionprognosis

Identifiers

PMID40141746
PMCPMC11943662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.