ReviewLife (Basel, Switzerland)2025
Micro- and Nano-Plastic-Induced Adverse Health Effects on Lungs and Kidneys Linked to Oxidative Stress and Inflammation.
Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Molecular and Cellular Effects of Microplastics and Nanoplastics in the Pathogenesis of Cardiovascular, Nervous, Urinary, Digestive, and Reproductive System Diseases: A Global Systematic Review.International journal of molecular sciences · 2025Pooled it
- Micro- and Nanoplastics as Environmental Stressors: Mechanistic Links Among Gut Dysbiosis, Inflammation, and Systemic Health Effects.Journal of xenobiotics · 2026Review
- Nanoplastic Pollution of Human Bronchoalveolar Lavage Probed Based on Tip-Enhanced Raman Scattering.Sensors (Basel, Switzerland) · 2026Article
- Article
- Effects of micro and nano plastics on renal health.World journal of nephrology · 2026Review
- Micro- and Nanoplastics Exposure Across the Lifespan: One Health Implications for Aging and Longevity.Journal of xenobiotics · 2026Review
- Harmful Effects of Microplastics and Nanoplastics in Human Body Systems: A Systematic Review.Diseases (Basel, Switzerland) · 2026Review
- Article
- Environmental Pollution and Its Impact on Kidney Diseases: A Comprehensive Review of Current Evidence.Life (Basel, Switzerland) · 2026Review
- Polyethylene Microplastics Disrupt Cardiopulmonary Homeostasis via Oxidative Stress, Inflammatory Crosstalk, and Mitochondrial Dysfunction in Wistar Rats.Cardiovascular toxicology · 2026Article
- Differential morphological and physicochemical responses of polyvinyl chloride and Polyamide-12 micro- and nanoplastics to Fenton oxidation.The Science of the total environment · 2026Article
- Micro- and nanoplastics as environmental modifiers of neuroimmune dysfunction in Parkinson's disease.Frontiers in neuroscience · 2026Review
- Silent invaders: the role of MPs on epithelium inflammation and damage in airway diseases.Frontiers in allergy · 2026Review
- Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects.Toxics · 2025Review
- Environmental Nephrotoxicity Across the Life Course: Oxidative Stress Mechanisms and Opportunities for Early Intervention.Antioxidants (Basel, Switzerland) · 2025Review
- Prospects and problems in enzyme immobilization methodology: comprehensive review.Biophysical reviews · 2025Review
- Risk Assessment of Microplastics in Humans: Distribution, Exposure, and Toxicological Effects.Polymers · 2025Review
- Forever particles: histochemistry in the plasticene age.European journal of histochemistry : EJH · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Micro- and nano-plastics (MNPs) are small plastic particles that result from the breakdown of larger plastics. They are widely dispersed in the environment and pose a threat to wildlife and humans. MNPs are present in almost all everyday items, including food, drinks, and household products. Air inhalation can also lead to exposure to MNPs. Research in animals indicates that once MNPs are absorbed, they can spread to various organs, including the liver, spleen, heart, lungs, thymus, reproductive organs, kidneys, and even the brain by crossing the blood-brain barrier. Furthermore, MPs can transport persistent organic pollutants or heavy metals from invertebrates to higher levels in the food chain. When ingested, the additives and monomers that comprise MNPs can disrupt essential biological processes in the human body, thereby leading to disturbances in the endocrine and immune systems. During the 2019 coronavirus (COVID-19) pandemic, there was a significant increase in the global use of polypropylene-based face masks, leading to insufficient waste management and exacerbating plastic pollution. This review examines the existing research on the impact of MNP inhalation on human lung and kidney health based on in vitro and in vivo studies. Over the past decades, a wide range of studies suggest that MNPs can impact both lung and kidney tissues under both healthy and diseased conditions. Therefore, this review emphasizes the need for additional studies employing multi-approach analyses of various associated biomarkers and mechanisms to gain a comprehensive and precise understanding of the impact of MNPs on human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.