Evidence map›Paper›PMID 40141721›Full record

ArticleLife (Basel, Switzerland)2025

The Golden Year? Early Intervention Yields Superior Outcomes in Chronic Pelvic Pain with Pudendal Neuralgia: A Comparative Analysis of Early vs. Delayed Treatment.

Alexandru Ciudin, Albert Carrion, Rosa Regue, Alfredo Rodriguez, Eduardo Garcia-Cruz, Diana Finkelstein, Claudia Mercader, Cristian Toma, Razvan Popescu, Cristian Persu and 4 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexandru CiudinInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.ORCID 0000-0002-0091-9688
Albert CarrionInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.ORCID 0000-0002-4639-1532
Rosa RegueInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Alfredo RodriguezInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Eduardo Garcia-CruzInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Diana FinkelsteinInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Claudia MercaderInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Cristian TomaUrology Department, Faculty of Medicine, "Prof. Dr. Th. Burghele" Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 061344 Bucharest, Romania.ORCID 0000-0003-4396-8081
Razvan PopescuUrology Department, Faculty of Medicine, "Prof. Dr. Th. Burghele" Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 061344 Bucharest, Romania.ORCID 0000-0002-6614-2816
Cristian PersuUrology Department, Faculty of Medicine, "Prof. Dr. Th. Burghele" Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 061344 Bucharest, Romania.ORCID 0000-0003-4530-684X
Sergi ColomInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.ORCID 0000-0003-1560-6075
Narcis CampsInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
Ramon SerrateInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.
María José RibalInstitut de Urologia Serrate Ribal, 08017 Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pelvic pain (CPP) associated with pudendal neuralgia (PN) significantly impacts quality of life (QoL). Pudendal nerve infiltration is a recognized treatment, but the optimal timing of intervention remains unclear.

methodsThis prospective study included 81 patients diagnosed with PN and treated with pudendal nerve infiltrations. Outcomes were assessed using the Visual Analog Scale (VAS), Spanish Pain Questionnaire (CDE-McGill), and the SF-12 health survey. Significant improvement was defined as a VAS reduction > 4 points and a QoL increase > 15 points. An ROC curve analysis identified a 13-month time-to-treatment threshold (sensitivity 78%, specificity 72%), categorizing patients into early (

resultsThe early treatment group showed significantly greater reductions in VAS scores (5.4 vs. 3.4 points,

conclusionsEarly intervention in PN significantly improves pain, QoL, and reduces reinfiltration and medication reliance, supporting timely treatment for optimal outcomes.

Indexed as

chronic pelvic painpudendal nerve infiltrationpudendal neuralgiatime to treatment

Identifiers

PMID40141721
PMCPMC11944006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.