Evidence map›Paper›PMID 40141710›Full record

ArticleLife (Basel, Switzerland)2025

Seasonal Changes in Thyrotropin and Thyroid Hormones in Women of Reproductive Age.

Sevgül Fakı, Abbas Ali Tam, Pervin Demir, Didem Özdemir, Fatma Neslihan Çuhacı Seyrek, Ekin Yiğit Köroğlu, Oya Topaloğlu, Reyhan Ersoy, Bekir Çakır

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Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Sevgül FakıDepartment of Endocrinology and Metabolism, Ankara Bilkent City Hospital, 6800 Ankara, Turkey.ORCID 0000-0003-1856-1263
Abbas Ali TamDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.
Pervin DemirDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.ORCID 0000-0002-6652-0290
Didem ÖzdemirDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.
Fatma Neslihan Çuhacı SeyrekDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.
Ekin Yiğit KöroğluDepartment of Endocrinology and Metabolism, Ankara Bilkent City Hospital, 6800 Ankara, Turkey.ORCID 0000-0003-3895-5817
Oya TopaloğluDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.
Reyhan ErsoyDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.
Bekir ÇakırDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara Yıldırım Beyazıt University, 6800 Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid hormones are essential for the proper functioning of the female reproductive system. Seasonal changes in thyroid hormones in women of reproductive age are not fully understood. we aimed to investigate seasonal changes in thyrotrophin and thyroid hormones in women of reproductive age.

methodsApproximately 75,000 TSH and thyroid hormone levels measured in 32,935 women between 2019 and 2023 were evaluated on a monthly and seasonal basis. The analysis of means (ANOM) method was utilized to compare the mean transformed rank of each group or the overall mean transformed rank for TSH, FT3, and FT4 values across months and seasons.

resultsThe differences from the maximum to minimum median values were 13.3% for TSH, 5.2% for free T3, and 5.9% for free T4. TSH levels were significantly lower in summer and autumn and higher in winter and spring than the overall transformed mean. The rate of individuals with TSH levels below 2.5 mIU/L was higher in summer and autumn than in spring and winter.

conclusionsTSH varies seasonally in women of reproductive age. It is appropriate to consider the season as well as other parameters that affect thyroid functions while evaluating thyroid hormones.

Indexed as

reproductive ageseasonal changesthyroid hormonesthyroid stimulating hormone

Identifiers

PMID40141710
PMCPMC11943981

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