Evidence map›Paper›PMID 40141554›Full record

ArticleMaterials (Basel, Switzerland)2025

New Biocompatible Cyanoacrylate and Polylactic Acid Hemostatic Patch: An In Vivo Proof of Concept Study.

Alexandru Ilie-Ene, Victor Petru Tosa, Luciana-Madalina Gherman, Raluca Maria Pop, Lorena-Maria Hantig, Catalin Ovidiu Popa, George Calin Dindelegan

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandru Ilie-EneDepartment of Surgery, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0003-1893-1930
Victor Petru TosaMaterials Science and Engineering Department, Technical University of Cluj-Napoca, 103-105 Muncii Ave., 400641 Cluj-Napoca, Romania.
Luciana-Madalina GhermanExperimental Centre, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 Louis Pasteur Street, 400349 Cluj-Napoca, Romania.ORCID 0000-0002-8976-1011
Raluca Maria PopPharmacology, Toxicology and Clinical Pharmacology, Department of Morphofunctional Sciences, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0003-1899-5977
Lorena-Maria HantigDepartment of Surgery, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.
Catalin Ovidiu PopaMaterials Science and Engineering Department, Technical University of Cluj-Napoca, 103-105 Muncii Ave., 400641 Cluj-Napoca, Romania.ORCID 0000-0003-4188-1169
George Calin DindeleganDepartment of Surgery, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0003-1485-6654

Funding

Romanian Ministry of Research, Innovation, and Digitalization 9/06/12/2023
6 · The paper itself

Abstract

backgroundTraumatic injuries cause millions of deaths annually, with intra-abdominal hemorrhage as a leading cause. Achieving hemostasis remains challenging. This study evaluates the hemostatic properties of a novel biocompatible cyanoacrylate-polylactic acid patch.

methodsThirty-six male Wistar rats were randomized into three groups (control, study, and TachoSil

resultsIn the study group, a median time to hemostasis of 94 s was recorded, compared with 256 s for electrocautery (

conclusionsThe results demonstrated that the novel cyanoacrylate-polylactic acid patch achieved rapid hemostasis and was associated with reduced inflammatory responses compared with both electrocautery and TachoSil

Indexed as

cyanoacrylateexperimental liver resection modelhemostatic materialpolylactic acidtopical hemostasis

Identifiers

PMID40141554
PMCPMC11943873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.