Evidence map›Paper›PMID 40141457›Full record

ArticleInternational journal of molecular sciences2025

Acute Effects of the Psychedelic Phenethylamine 25I-NBOMe in C57BL/6J Male Mice.

Sabrine Bilel, Cristina Miliano, Giorgia Corli, Marta Bassi, Massimo Trusel, Raffaella Tonini, Maria Antonietta De Luca, Matteo Marti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sabrine BilelDepartment of Translational Medicine, Section of Legal Medicine and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.
Cristina MilianoDepartment of Biomedical Sciences, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-4042-468X
Giorgia CorliDepartment of Translational Medicine, Section of Legal Medicine and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-2973-2446
Marta BassiDepartment of Translational Medicine, Section of Legal Medicine and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0008-3753-4627
Massimo TruselNeuromodulation of Cortical and Subcortical Circuits Laboratory, Neuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Raffaella ToniniNeuromodulation of Cortical and Subcortical Circuits Laboratory, Neuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Maria Antonietta De LucaDepartment of Biomedical Sciences, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-2647-4859
Matteo MartiDepartment of Translational Medicine, Section of Legal Medicine and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-8751-2882

Funding

Anti-Drug Policies Department, Presidency of the Council of Ministers, Italy project: "Effects of NPS: development of a multicentre research for the information enhancement of the Early Warning System" to M.M.RAS-FSC 2018 Codice intervento: RC_CRP_034; CUP RASSR03071; project: "Multidisciplinary preclinical study on NPS and evaluation of their behavioral and neurophysiological effects related to age and sex" to M.A.D.L.the Anti-Drug Policies Department, Presidency of the Council of Ministers, Italy project: "Implementation of the identification and study of the effects of NPS: Development of a multicentric research to strengthen the database of the National Monitoring Centre for Drug Ad-diction and the Early Warning System" to M.M. and M.A.D.L.; CUPUniversity of Ferrara FAR2022 to M.M.University of Ferrara FAR2023 to M.M.
6 · The paper itself

Abstract

25I-NBOMe (4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl) phenethylamine) is a synthetic psychedelic compound abused for its ambiguous legal state as a counterfeit lysergic acid diethylamide (LSD). 25I-NBOMe acts as a selective agonist of 5HT

Indexed as

DimethoxyphenylethylamineHallucinogensPhenethylaminesAnimalsBehavior, AnimalDopamineMaleMiceMice, Inbred C57BLNucleus AccumbensPrefrontal Cortex2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamineDimethoxyphenylethylamineDopamineHallucinogensPhenethylamines25I-NBOMe5HT2A agonistbehavioral testsdopamine transmissionLTDLTPmicrodialysisprepulse inhibitionsynaptic plasticity

Identifiers

PMID40141457
PMCPMC11943083

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.