Evidence map›Paper›PMID 40141446›Full record

ArticleInternational journal of molecular sciences2025

A Two-Phage Cocktail Modulates Gut Microbiota Composition and Metabolic Profiles in an Ex Vivo Colon Model.

Sthefhany Nohemí Rodríguez-Arellano, Jean Pierre González-Gómez, Bruno Gomez-Gil, Marisela González-Ávila, Juan Ramón Palomera-Hernández, Elisa Barrón-Cabrera, Marcela de Jesús Vergara-Jiménez, Cristobal Chaidez

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sthefhany Nohemí Rodríguez-ArellanoFacultad de Ciencias de la Nutrición y Gastronomía, Universidad Autónoma de Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0009-0009-4549-4386
Jean Pierre González-GómezLaboratorio Nacional para la Investigación en Inocuidad Alimentaria (LANIIA), Centro de Investigación en Alimentación y Desarrollo, A.C. (CIAD), Culiacan 80110, Sinaloa, Mexico.ORCID 0000-0003-2994-4358
Bruno Gomez-GilCentro de Investigación en Alimentación y Desarrollo, A.C. (CIAD), Unidad Mazatlán en Acuicultura y Manejo Ambiental, Mazatlan 82112, Sinaloa, Mexico.ORCID 0000-0002-3695-3597
Marisela González-ÁvilaMedical and Pharmaceutical Biotechnology, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. (CIATEJ), Guadalajara 44270, Jalisco, Mexico.ORCID 0000-0001-7799-2587
Juan Ramón Palomera-HernándezMedical and Pharmaceutical Biotechnology, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. (CIATEJ), Guadalajara 44270, Jalisco, Mexico.ORCID 0009-0003-6123-7650
Elisa Barrón-CabreraFacultad de Ciencias de la Nutrición y Gastronomía, Universidad Autónoma de Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0002-4552-1606
Marcela de Jesús Vergara-JiménezFacultad de Ciencias de la Nutrición y Gastronomía, Universidad Autónoma de Sinaloa, Culiacan 80019, Sinaloa, Mexico.
Cristobal ChaidezLaboratorio Nacional para la Investigación en Inocuidad Alimentaria (LANIIA), Centro de Investigación en Alimentación y Desarrollo, A.C. (CIAD), Culiacan 80110, Sinaloa, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage therapy is a promising approach for targeting antibiotic-resistant bacteria and modulating gut microbiota in metabolic diseases such as obesity. This study evaluated the impact of a two-phage cocktail on an ex vivo colonic simulation model of gut microbiota derived from obese individuals, both in its normalized state and after enrichment with

Indexed as

BacteriophagesColonGastrointestinal MicrobiomeMetabolomePhage TherapyEnterobacter cloacaeFatty Acids, VolatileHumansMaleObesityRNA, Ribosomal, 16SFatty Acids, VolatileRNA, Ribosomal, 16Sbacteriophagemetabarcoding 16S rRNAmicrobiota modulationphage therapyshort-chain fatty acid

Identifiers

PMID40141446
PMCPMC11942677

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.