Evidence map›Paper›PMID 40141445›Full record

ArticleInternational journal of molecular sciences2025

TBG096 Ameliorates Memory Deficiency in AD Mouse Model via Promoting Neurogenesis and Regulation of Hsc70/HK2/PKM2/LAMP2A Signaling Pathway.

Danni Chen, Opeyemi B Fasina, Jiahui Lin, Jiayuan Zeng, Majid Manzoor, Hiroshi Ohno, Lan Xiang, Jianhua Qi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danni ChenCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.
Opeyemi B FasinaCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.
Jiahui LinCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.ORCID 0009-0009-2540-7089
Jiayuan ZengCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.
Majid ManzoorCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.
Hiroshi OhnoRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehirocho, Tsutumiku, Yokohama 230-0045, Japan.ORCID 0000-0001-8776-9661
Lan XiangCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.ORCID 0000-0001-6595-2836
Jianhua QiCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.

Funding

National Key R&D Program of China 2022YFE0104000
6 · The paper itself

Abstract

In previous studies, we isolated a series of novel gentisides with nerve growth factor (NGF)-mimic activities from

Indexed as

Alzheimer DiseaseMemory DisordersNeurogenesisSignal TransductionAnimalsDiet, High-FatDisease Models, AnimalHSC70 Heat-Shock ProteinsMaleMembrane ProteinsMiceMice, Inbred C57BLPyruvate KinaseHSC70 Heat-Shock ProteinsMembrane ProteinsPyruvate KinaseAlzheimer’s diseaseheat-shock cognate protein 70nerve growth factorneurogenesis

Identifiers

PMID40141445
PMCPMC11943016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.