Evidence map›Paper›PMID 40141415›Full record

ReviewInternational journal of molecular sciences2025

Role of PARP Inhibitors: A New Hope for Breast Cancer Therapy.

Kamalendu De, Malabendu Jana, Bhabadeb Chowdhury, Gloria M Calaf, Debasish Roy

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kamalendu DeDepartment of Biological Sciences (Botany), Midnapore City College, Midnapore 721129, West Bengal, India.
Malabendu JanaDepartment of Neurological Science, Rush University School of Medicine, Chicago, IL 773, USA.
Bhabadeb ChowdhuryHIV Dynamics and Replication Program, National Institute of Health, Frederick, MD 21702, USA.
Gloria M CalafInstituto de Alta Investigación, Universidad de Tarapacá, Arica 1000000, Chile.ORCID 0000-0003-3542-296X
Debasish RoyDepartment of Natural Sciences, Hostos College of The City University of New York, Bronx, NY 718, USA.

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT/ANID) FONDECYT 1231537
6 · The paper itself

Abstract

Tumors formed by the unchecked growth of breast cells are known as breast cancer. The second most frequent cancer in the world is breast cancer. It is the most common cancer among females. In 2022, 2,296,840 women were diagnosed with breast cancer. The therapy of breast cancer is evolving through the development of Poly (ADP-ribose) polymerase (PARP) inhibitors, which are offering people with specific genetic profiles new hope as research into the disease continues. It focuses on patients with

Indexed as

Antineoplastic AgentsBreast NeoplasmsPoly(ADP-ribose) Polymerase InhibitorsBRCA1 ProteinBRCA2 ProteinFemaleHumansMutationAntineoplastic AgentsBRCA1 ProteinBRCA2 ProteinPoly(ADP-ribose) Polymerase InhibitorsBRCA1BRCA2breast cancerPARP inhibitorstherapytumors

Identifiers

PMID40141415
PMCPMC11942994

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.