Evidence map›Paper›PMID 40141400›Full record

ArticleInternational journal of molecular sciences2025

Impact of the Human Leukocyte Antigen Complex on Idiopathic Pulmonary Fibrosis Development and Progression in the Sardinian Population.

Marina Serra, Stefano Mocci, Silvia Deidda, Maurizio Melis, Luchino Chessa, Sara Lai, Erika Giuressi, Caterina Mereu, Celeste Sanna, Michela Lorrai and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marina SerraOncology and Molecular Pathology Unit, Department of Biomedical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0001-6916-882X
Stefano MocciMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Silvia DeiddaPneumology Unit, R. Binaghi Hospital, 09100 Cagliari, Italy.ORCID 0009-0004-6879-2400
Maurizio MelisAART-ODV (Association for the Advancement of Research on Transplantation), 09131 Cagliari, Italy.ORCID 0000-0002-5857-781X
Luchino ChessaLiver Unit, Department of Internal Medicine, University Hospital of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-9474-0995
Sara LaiMedical Genetics, R. Binaghi Hospital, 09100 Cagliari, Italy.ORCID 0000-0002-8040-0631
Erika GiuressiMedical Genetics, R. Binaghi Hospital, 09100 Cagliari, Italy.
Caterina MereuMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0009-0006-2588-6807
Celeste SannaMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Michela LorraiMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0009-0002-6660-1784
Michela MurgiaMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Federica CannasMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Alessia MasciaOncology and Molecular Pathology Unit, Department of Biomedical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0009-0000-2881-7408
Andrea PerraOncology and Molecular Pathology Unit, Department of Biomedical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-8098-899X
Roberto LitteraAART-ODV (Association for the Advancement of Research on Transplantation), 09131 Cagliari, Italy.ORCID 0000-0003-3143-3792
Sabrina GiglioMedical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-3954-326X

Funding

Italian Ministry of University and Research CUP F53C22000750006
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the disruption of the alveolar and interstitial architecture due to extracellular matrix deposition. Emerging evidence suggests that genetic susceptibility plays a crucial role in IPF development. This study explores the role of human leukocyte antigen (

Indexed as

HLA AntigensIdiopathic Pulmonary FibrosisAgedAllelesDisease ProgressionFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHaplotypesHumansItalyMaleMiddle AgedHLA AntigensgeneticsHLAidiopathic pulmonary fibrosisILDsIPFSardinia

Identifiers

PMID40141400
PMCPMC11942992

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.