Evidence map›Paper›PMID 40141343›Full record

ArticleInternational journal of molecular sciences2025

Screening and Application of DNA Markers for Novel Quality Consistency Evaluation in

Siyuan Cai, Xuejiao Liao, Yidan Xi, Yang Chu, Shuang Liu, Hang Su, Deqiang Dou, Jiang Xu, Shuiming Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siyuan CaiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Xuejiao LiaoState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0001-7101-9655
Yidan XiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yang ChuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shuang LiuShanxi Institute of Functional Foods, Shanxi Agricultural University, Taiyuan 030031, China.
Hang SuNortheast Asia Research Institute of Traditional Chinese Medicine, Key Laboratory of Active Substances and Biological Mechanisms of Ginseng Efficacy, Ministry of Education, Jilin Provincial Key Laboratory of Bio-Macromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China.
Deqiang DouCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.ORCID 0000-0003-0571-3416
Jiang XuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shuiming XiaoState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0003-4925-0839

Funding

Fundamental Research Funds for the Central Public Welfare Research Institutes ZZ13-YQ-047National Key Research and Development Program of China 2023YFC3504000Scientific and technological innovation project of China Academy of Chinese Medical Sciences CI2023E002
6 · The paper itself

Abstract

Quality control remains a challenge in traditional Chinese medicine (TCM). This study introduced a novel genetic-based quality control method for TCM. Genetic variations in ginseng were evaluated across whole-genome, chloroplast genome, and ITS2 DNA barcode dimensions. Significant genetic variations were found in whole-genome comparison, leading to the use of inter-simple sequence repeat markers to assess the genetic diversity of ginseng decoction pieces (PG), garden ginseng (GG), and ginseng under forest (FG). Fingerprints of ginseng samples revealed instability within some batches. These evaluations were transformed into information entropy to calculate the size of Hardy-Weinberg equilibrium population (HWEP). FG had significantly higher genetic and chemical minimum HWEP than GG (

Indexed as

DNA, PlantPanaxGenetic MarkersGenetic VariationGenome, ChloroplastMedicine, Chinese TraditionalMicrosatellite RepeatsPolymorphism, GeneticQuality ControlDNA, PlantGenetic Markersgenetic polymorphismHWEPPanax ginsengquality consistency

Identifiers

PMID40141343
PMCPMC11942579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.