Evidence map›Paper›PMID 40141310›Full record

ArticleInternational journal of molecular sciences2025

Plasma Exosomal-Derived SERPINA1 and GNAI2 Downregulation as Potential Diagnostic Biomarkers of Kawasaki Disease with Coronary Artery Aneurysms.

Yang Zheng, Baoling Bai, Zhimiao Wei, Mingming Zhang, Qin Zhang, Xiaohui Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yang ZhengDepartment of Cardiovascular Medicine, Children's Hospital Capital Institute of Pediatrics, Peking Union Medical College Graduate School, Beijing 100020, China.ORCID 0009-0000-1219-9828
Baoling BaiBeijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
Zhimiao WeiDepartment of Cardiovascular Medicine, Children's Hospital Capital Institute of Pediatrics, Beijing 100020, China.
Mingming ZhangDepartment of Cardiovascular Medicine, Children's Hospital Capital Institute of Pediatrics, Beijing 100020, China.
Qin ZhangBeijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
Xiaohui LiDepartment of Cardiovascular Medicine, Children's Hospital Capital Institute of Pediatrics, Peking Union Medical College Graduate School, Beijing 100020, China.

Funding

Capital Institute of Pediatrics research funding JHYJ-2025-03National Natural Science Foundation of China 82370511
6 · The paper itself

Abstract

Kawasaki disease (KD) with coronary artery aneurysms (CAAs) is currently the primary cause of childhood acquired heart disease with an unclear pathogenesis. We established five groups for the discovery of differentially expressed proteins (DEPs): healthy control, febrile control, KD without CAAs, KD with small and medium CAAs, and KD with giant CAAs (

Indexed as

alpha 1-AntitrypsinCoronary AneurysmExosomesGTP-Binding Protein alpha Subunits, Gi-GoMucocutaneous Lymph Node SyndromeBiomarkersCase-Control StudiesChildChild, PreschoolDown-RegulationFemaleHumansInfantMalealpha 1-AntitrypsinBiomarkersGTP-Binding Protein alpha Subunits, Gi-GoSERPINA1 protein, humancoronary artery aneurysms (CAAs)exosomeKawasaki disease (KD)proteomics

Identifiers

PMID40141310
PMCPMC11942354

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.