Evidence map›Paper›PMID 40141300›Full record

ReviewInternational journal of molecular sciences2025

Decoding Liver Fibrosis: How Omics Technologies and Innovative Modeling Can Guide Precision Medicine.

Gabriele Codotto, Benedetta Blarasin, Claudio Tiribelli, Cristina Bellarosa, Danilo Licastro

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriele CodottoDepartment of Life Science and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0004-6184-6242
Benedetta BlarasinDepartment of Life Science, University of Trieste, 34127 Trieste, Italy.
Claudio TiribelliFondazione Italiana Fegato ONLUS-Italian Liver Foundation NPO, 34149 Trieste, Italy.ORCID 0000-0001-6596-7595
Cristina BellarosaFondazione Italiana Fegato ONLUS-Italian Liver Foundation NPO, 34149 Trieste, Italy.ORCID 0000-0002-2865-2575
Danilo LicastroAREA Science Park, 34149 Trieste, Italy.

Funding

QuB - Quantum Behavior in Biological Function funded by MUR CUP J95F21002820001
6 · The paper itself

Abstract

The burden of chronic liver disease (CLD) is dramatically increasing. It is estimated that 20-30% of the population worldwide is affected by CLD. Hepatic fibrosis is a symptom common to all CLDs. Although it affects liver functional activities, it is a reversible stage if diagnosed at an early stage, but no resolutive therapy to contrast liver fibrosis is currently available. Therefore, efforts are needed to study the molecular insights of the disease. Emerging cutting-edge fields in cellular and molecular biology are introducing innovative strategies. Spatial and single-cell resolution approaches are paving the way for a more detailed understanding of the mechanisms underlying liver fibrosis. Cellular models have been generated to recapitulate the

Indexed as

GenomicsLiver CirrhosisPrecision MedicineAnimalsHumansInduced Pluripotent Stem CellsModels, BiologicalOrganoidsProteomicsiPSC-derived liver cellsliver fibrosisorganoidspersonalized medicinePLCSsingle-cell RNA-sequencingspatial transcriptomics

Identifiers

PMID40141300
PMCPMC11942424

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.