Evidence map›Paper›PMID 40141279›Full record

ArticleInternational journal of molecular sciences2025

Notch Is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth.

Dylan J Guerin, Belen Gutierrez, Baoyi Zhang, Kelly Ai-Sun Tseng

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Temporal Transcriptomic Profiling of the DevelopingbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dylan J GuerinSchool of Life Sciences, University of Nevada, Las Vegas, NV 89154, USA.
Belen GutierrezSchool of Life Sciences, University of Nevada, Las Vegas, NV 89154, USA.
Baoyi ZhangSchool of Life Sciences, University of Nevada, Las Vegas, NV 89154, USA.
Kelly Ai-Sun TsengSchool of Life Sciences, University of Nevada, Las Vegas, NV 89154, USA.ORCID 0000-0001-5133-6696

Funding

Regulation of Eye Regrowth in Xenopus laevmisR16GM146672 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI TSENG, KELLY · 2022 to 2025
$847k
NASA 80NSSC20M0043NIGMS NIH HHS R16 GM146672NIH HHS GM146672NSF 1757316NSF IIA1301726NSF OIA2148788
6 · The paper itself

Abstract

The ability of an organism to regrow tissues is regulated by various signaling pathways. One such pathway that has been studied widely both in the context of regeneration and development is the Notch signaling pathway. Notch is required for the development of the eye and regeneration of tissues in multiple organisms, but it is unknown if Notch plays a role in the regulation of

Indexed as

EyeNeural Stem CellsReceptor, Notch1Receptors, NotchRegenerationRetinaXenopus laevisXenopus ProteinsAnimalsCell DifferentiationCell ProliferationSignal TransductionVacuolar Proton-Translocating ATPasesReceptor, Notch1Receptors, NotchVacuolar Proton-Translocating ATPasesXenopus Proteinseyeneural stem cellsNotchregenerationregrowthretinaRPCsV-ATPaseXenopus

Identifiers

PMID40141279
PMCPMC11942531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.