Evidence map›Paper›PMID 40141255›Full record

ArticleInternational journal of molecular sciences2025

HIF-3α/PPAR-γ Regulates Hypoxia Tolerance by Altering Glycolysis and Lipid Synthesis in Blunt Snout Bream (

Minggui Jiang, Jing Huang, Xing Guo, Wen Fu, Liangyue Peng, Yang Wang, Wenbin Liu, Jinhui Liu, Li Zhou, Yamei Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Minggui JiangCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Jing HuangCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Xing GuoCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Wen FuCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Liangyue PengCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Yang WangState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0003-0727-607X
Wenbin LiuCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Jinhui LiuCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Li ZhouState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Yamei XiaoCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.

Funding

Hunan Province Postgraduate Scientific Research Innovation Project CX20240543National Key Research and Development Program of China 2018YFD0901202National Natural Science Foundation of China U23A20246
6 · The paper itself

Abstract

Hypoxic stress causes cell damage and serious diseases in organisms, especially in aquatic animals. It is important to elucidate the changes in metabolic function caused by hypoxia and the mechanisms underlying these changes. This study focuses on the low oxygen tolerance feature of a new blunt snout bream strain (GBSBF1). Our data show that GBSBF1 has a different lipid and carbohydrate metabolism pattern than wild-type bream, with altering glycolysis and lipid synthesis. In GBSBF1, the expression levels of

Indexed as

CyprinidaeFish ProteinsGlycolysisHypoxiaPPAR gammaAnimalsLipid MetabolismOxygenFish ProteinsOxygenPPAR gammablunt snout breamenergy metabolismHIF/PPAR-γ signaling pathwayhypoxia tolerance

Identifiers

PMID40141255
PMCPMC11942064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.