ArticleInternational journal of molecular sciences2025
Search for Disease-Specific Genetic Markers Originated from the Vitamin D Binding Protein Gene Polymorphisms in the Multiple Sclerosis Cohort in the Latvian Population.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors.
Jolanta KalninaGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.
Ilva TrapinaGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.ORCID 0000-0002-2165-4770
Samanta PlavinaGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.ORCID 0009-0001-0984-4002
Elina LeonovaGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.
Jegors ParamonovsGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.
Nikolajs SjaksteGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.
Natalia ParamonovaGenomic and Bioinformatic Laboratory, The Department of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, the University of Latvia, LV-1004 Riga, Latvia.ORCID 0000-0001-6375-3331
Funding
Postdoc project of UL No. 1.1.1.2/VIAA/4/20/718 "The role of vitamin D and its receptor gene polymorphisms in the modulation of intestinal inflammation in patients with relapsing and progressive forms of multiple sclerosis"
6 · The paper itself
Abstract
Vitamin D is crucial for immune regulation, and its deficiency is linked to multiple sclerosis (MS). The GC gene encodes Vitamin D Binding Protein (VDBP), which regulates vitamin D transport and bioavailability. This study examines the association of
Indexed as
Genetic Predisposition to DiseaseMultiple SclerosisPolymorphism, Single NucleotideVitamin D-Binding ProteinAdultAllelesCase-Control StudiesFemaleGene FrequencyGenetic MarkersGenotypeHaplotypesHumansLatviaMaleMiddle Aged25-hydroxyvitamin DGC protein, humanGenetic MarkersVitamin DVitamin D-Binding Protein25-hydroxyvitamin D (25(OH)D)multiple sclerosisrs4588 (Thr436Lys)rs7041 (Asp432Glu)single Nucleotide Polymorphisms (SNPs)Vitamin D Binding Protein (VDBP)
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Search for Disease-Specific Genetic Markers Originated from the Vitamin D Binding Protein Gene Polymorphisms in the Multiple Sclerosis Cohort in the Latvian Population. · full record | OpenQuestion