Evidence map›Paper›PMID 40141145›Full record

ReviewInternational journal of molecular sciences2025

Gut Microbiota Serves as a Crucial Independent Biomarker in Inflammatory Bowel Disease (IBD).

Bharti Sharma, George Agriantonis, Kate Twelker, Danielle Ebelle, Samantha Kiernan, Maham Siddiqui, Aditi Soni, Sittha Cheerasarn, Whenzdjyny Simon, Winston Jiang and 9 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. The MOF-Microbiome Axis: a New Paradigm for Precision Nanomedicine.Probiotics and antimicrobial proteins · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Deconvolving Phylogenetic Distance Mixtures.bioRxiv : the preprint server for biology · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Frontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bharti SharmaDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.ORCID 0000-0001-8477-6225
George AgriantonisDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Kate TwelkerDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.ORCID 0009-0008-6162-1720
Danielle EbelleDepartment of Medicine, St. George's University, Grenada FZ818, West Indies.
Samantha KiernanDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Maham SiddiquiDepartment of Medicine, St. George's University, Grenada FZ818, West Indies.
Aditi SoniDepartment of Medicine, St. George's University, Grenada FZ818, West Indies.
Sittha CheerasarnDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Whenzdjyny SimonDepartment of Medicine, St. George's University, Grenada FZ818, West Indies.
Winston JiangDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Angie CardonaDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Jessica ChapeletDepartment of Medicine, St. George's University, Grenada FZ818, West Indies.
Alexandra Z AgathisDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Alejandro GamboaDepartment of Medicine, Medical University of the Americas, Devens, MA 01434, USA.
Jasmine DaveDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Juan MestreDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Navin D BhatiaDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Zahra ShaefeeDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.
Jennifer WhittingtonDepartment of Surgery, NYC Health and Hospitals-Elmhurst, New York, NY 11373, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD), ulcerative colitis (UC), and IBD unclassified (IBD-U), is a complex intestinal disorder influenced by genetic, environmental, and microbial factors. Recent evidence highlights the gut microbiota as a pivotal biomarker and modulator in IBD pathogenesis. Dysbiosis, characterized by reduced microbial diversity and altered composition, is a hallmark of IBD. A consistent decrease in anti-inflammatory bacteria, such as

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesAnimalsBiomarkersDysbiosisHumansBiomarkersCrohn’s diseaseglycosylationgut microbiotainflammatory bowel diseasemorphogenpodoplaninulcerative colitis

Identifiers

PMID40141145
PMCPMC11942158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.