Evidence map›Paper›PMID 40141134›Full record

ArticleInternational journal of molecular sciences2025

Novel Bioactive Resin Coating with Calcium Phosphate Nanoparticles for Antibacterial and Remineralization Abilities to Combat Tooth Root Caries.

Nader Almutairi, Abdullah Alhussein, Mohammad Alenizy, Ibrahim Ba-Armah, Heba Alqarni, Thomas W Oates, Radi Masri, Gary D Hack, Jirun Sun, Michael D Weir and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nader AlmutairiDental Biomedical Sciences PhD Program, Graduate School, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0002-7197-8239
Abdullah AlhusseinDepartment of Restorative Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.ORCID 0000-0002-7926-2673
Mohammad AlenizyDental Biomedical Sciences PhD Program, Graduate School, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0002-7850-9961
Ibrahim Ba-ArmahDental Biomedical Sciences PhD Program, Graduate School, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0002-3524-2515
Heba AlqarniDental Biomedical Sciences PhD Program, Graduate School, University of Maryland, Baltimore, MD 21201, USA.
Thomas W OatesDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Radi MasriDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Gary D HackDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Jirun SunThe ADA Forsyth Institute, Cambridge, MA 02142, USA.
Michael D WeirDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Hockin H K XuDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Funding

Hydrolysis-resistant resin networks for durable and multifunctional dental restorationsR01DE033442 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI Jirun Sun, HUAKUN XU · 2024 to 2026
$1.4M
NIDCR NIH HHS R01 DE033442NIH HHS 1R01DE033442-01A1
6 · The paper itself

Abstract

Tooth root caries account for 10.1% of all dental caries in the USA. This study developed a multifunctional resin coating with calcium (Ca) and phosphate (P) ion release and antibacterial properties to combat root caries. The effects of nano-sized amorphous calcium phosphate (NACP) and dimethylaminohexadecyl methacrylate (DMAHDM) on mechanical, physical, and antibacterial properties against

Indexed as

Anti-Bacterial AgentsCalcium PhosphatesNanoparticlesRoot CariesTooth RemineralizationDental PulpFibroblastsHumansMethacrylatesStem CellsStreptococcus mutansamorphous calcium phosphateAnti-Bacterial Agentscalcium phosphateCalcium PhosphatesMethacrylatesantibacterial polymersantibiofilmcoatingpolymer synthesisremineralizationresinroot caries

Identifiers

PMID40141134
PMCPMC11941978

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.