Evidence map›Paper›PMID 40141106›Full record

ReviewInternational journal of molecular sciences2025

Imaging of Thromboinflammation by Multispectral

Sebastian Temme, Patricia Kleimann, Zeynep-Büsra Tiren, Pascal Bouvain, Arthur Zielinski, William Dollmeyer, Sarah Poth, Juliana Görges, Ulrich Flögel

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sebastian TemmeDepartment of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0000-0002-8807-2767
Patricia KleimannExperimental Cardiovascular Imaging, Institute of Molecular Cardiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0009-0009-8917-4229
Zeynep-Büsra TirenDepartment of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Pascal BouvainExperimental Cardiovascular Imaging, Institute of Molecular Cardiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Arthur ZielinskiDepartment of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
William DollmeyerDepartment of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Sarah PothExperimental Cardiovascular Imaging, Institute of Molecular Cardiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Juliana GörgesDepartment of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Ulrich FlögelExperimental Cardiovascular Imaging, Institute of Molecular Cardiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0000-0001-7181-4392

Funding

German Research Foundation (DFG) FL 303/6-2German Research Foundation (DFG) INST 208/764-1 FUGGGerman Research Foundation (DFG) SFB 1116German Research Foundation (DFG) TE 1209/1-2German Research Foundation (DFG) TRR 259
6 · The paper itself

Abstract

The close interplay between thrombotic and immunologic processes plays an important physiological role in the immune defence after tissue injury and has the aim to reduce damage and to prevent the spread of invading pathogens. However, the uncontrolled or exaggerated activation of these processes can lead to pathological thromboinflammation. Thromboinflammation has been shown to worsen the outcome of cardiovascular, autoinflammatory, or even infectious diseases. Imaging of thromboinflammation is difficult because many clinically relevant imaging techniques can only visualize either inflammatory or thrombotic processes. One interesting option for the noninvasive imaging of thromboinflammation is multispectral

Indexed as

Fluorine-19 Magnetic Resonance ImagingInflammationMagnetic Resonance ImagingThromboinflammationThrombosisAnimalsHumans19F MRIfibrinFXIIIagpIIb/IIIamulticolor 19F MRImultispectral 19F MRIneutrophilsthromboinflammation

Identifiers

PMID40141106
PMCPMC11942564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.