Evidence map›Paper›PMID 40141040›Full record

ArticleInternational journal of molecular sciences2025

Next Generation Sequencing Analysis in Patients Affected by Parkinson's Disease and Correlation Between Genotype and Phenotype in Selected Clinical Cases.

Andrea Pilotto, Mattia Carini, Roberto Bresciani, Eugenio Monti, Fabiana Ferrari, Maria Antonia De Francesco, Alessandro Padovani, Giorgio Biasiotto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea PilottoNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Mattia CariniDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-7243-0673
Roberto BrescianiDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-7881-7550
Eugenio MontiDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-4742-7445
Fabiana FerrariPediatrics, Mother's and Baby's Health Department, Poliambulanza Foundation Hospital Institute, 25124 Brescia, Italy.
Maria Antonia De FrancescoDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0003-2221-6286
Alessandro PadovaniNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Giorgio BiasiottoDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-7495-7807

Funding

University of Brescia Ex 60% Biasiotto
6 · The paper itself

Abstract

Parkinson's Disease (PD) is the most frequent movement disorder and is second only to Alzheimer's Disease as the most frequent neurodegenerative pathology. Early onset Parkinson's disease (EOPD) is less common and may be characterized by genetic predisposition. NGS testing might be useful in the diagnostic assessment of these patients. A panel of eight genes (

Indexed as

High-Throughput Nucleotide SequencingParkinson DiseaseAdultAgedC9orf72 ProteinFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHemochromatosis ProteinHumansMaleMiddle AgedMutationPhenotypeC9orf72 ProteinC9orf72 protein, humanHemochromatosis Proteinclinical casegenetic backgroundNGSParkinson’s disease

Identifiers

PMID40141040
PMCPMC11942189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.