SynthesisSystematic reviews2025
The effect of lower limb rehabilitation robot on lower limb -motor function in stroke patients: a systematic review and meta-analysis.
Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07057700 (Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of BCI-based lower limb robots on lower limb function and cognition in stroke patients: a preliminary systematic review.Frontiers in human neuroscience · 2026Pooled it
- Robot-assisted rehabilitation for post-stroke balance and postural control: an umbrella review and evidence map of systematic reviews.Frontiers in neurology · 2026Pooled it
- The recovery of lower limb function in stroke patients: which sequence of transcranial direct current stimulation combined with lower limb rehabilitation robot is most effective-A randomized controlled trial.Journal of neuroengineering and rehabilitation · 2026Trial
- tDCS synchronous robotic training on lower-limb with post-stroke hemiplegia: a comparative study between synchronous and sequential group.Annals of medicine · 2026Article
- GaitIntent: A Kinematic Dataset Focusing on Steady-State to Transitional Locomotion for Lower-Limb Motion Rehabilitation.Scientific data · 2026Article
- Effects of Non-Suspended Robot-Assisted Ambulatory Training on Stroke Patients.Healthcare (Basel, Switzerland) · 2026Article
- Unveiling the Clinical Impact of Lower Limb Robotic Devices in Neurorehabilitation: An Umbrella Review.Annals of biomedical engineering · 2026Review
- Effects of exercise regimens on balance ability in older patients with osteoporosis: a systematic review and Bayesian network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe assessment and enhancement of lower limb motor function in hemiplegic patients is of paramount importance. The emergence of lower limb rehabilitation robots offers a promising avenue for improving motor function in these patients, addressing the limitations associated with traditional rehabilitation therapies. However, a consensus regarding their clinical effectiveness remains elusive. Consequently, the objective of this study is to systematically review the rehabilitation efficacy of lower limb rehabilitation robots on motor function in post-stroke hemiplegic patients, thereby providing robust clinical evidence to support their promotion and utilization.
methodsEight databases were examined between the start and April 2024. Patients with hemiplegia were included in randomized controlled trials to examine the effects of a lower limb rehabilitation robot on their motor function. Data extraction, risk of bias assessment, and study screening were carried out independently by two reviewers. Stata and Review Manager 5.3 were used for the meta-analysis. Sensitivity analysis was used to determine how reliable the findings were. To examine the origins of heterogeneity, meta-regression and subgroup analysis were employed.
resultsThis review comprised a total of 41 studies with 3279 participants. In one or more domains, the majority of the studies were rated as having a low or uncertain risk of bias. The study's findings demonstrated that the lower limb walking function, balance function, and ability to do activities of daily living improved more in the group receiving conventional rehabilitation (CR) + robot-assisted therapy (RT) than in the CR group. The Berg Balance Scale (BBS), which measures balance function, and the Fugl-Meyer scale (FMA), which measures lower limb motor function, were both better in the RT group than in the CR group. Sensitivity analysis proved that the findings were reliable. The sample size and publication years were found to be somewhat responsible for the heterogeneity, according to meta-regression analysis and subgroup analysis.
conclusionIn stroke patients with hemiplegia, the lower limb rehabilitation robot has demonstrated a certain level of clinical success in regaining lower limb function.
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Registered trials
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