ArticleEuropean journal of medical research2025
Pregnancy is influenced by more than just embryo ploidy: a retrospective study on preimplantation genetic testing.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Miscarriage history is not associated with embryonic aneuploidy in women under 38 years of age with recurrent pregnancy loss.Frontiers in endocrinology · 2026Article
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6 authors.
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Abstract
backgroundAssisted reproductive technology (ART) has been widely used to treat infertility for more than four decades, but its efficacy is still lower than expected. Therefore, further exploration of the factors that affect the pregnancy outcome of ART treatment is necessary. MATERIALS AND
methodsA retrospective study of chromosome rearrangement carrier couples who requested preimplantation genetic testing (PGT) for structural rearrangements at the Fourth Hospital of Shijiazhuang was conducted between February 2019 and December 2022. Multivariate logistic regression analysis was performed to determine the risk factors for pregnancy.
resultsIn total, 113 couples were transferred with a single euploid blastocyst, and 77 couples achieved pregnancy. Women with good-quality embryos transferred had a higher probability of pregnancy than women with poor-quality embryos transferred (OR 6.149, 95% CI 2.026-18.658). The chance of pregnancy was higher in women with a pregnancy history than in women without a pregnancy history (OR 3.181, 95% CI 1.157-8.747). The progesterone level on the day of trigger was positively associated with pregnancy (OR 2.605, 95% CI 1.226-5.538).
conclusionEmbryo quality is significantly associated with the pregnancy rate in patients treated with PGT. Embryo ploidy is just one of the factors affecting embryo development. Future studies should focus on the molecular mechanisms of embryo development and develop corresponding detection methods.
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