Evidence map›Paper›PMID 40140877›Full record

ReviewJournal of cardiothoracic surgery2025

Anal-cardiac reflex leading to coronary spasm and cardiac arrest during abdominoperineal excision of the rectum (MILES): case report and review of the literature.

Yimei Lin, Jingyi Wu, Junmei Wu, Juanlan Liu, Chao Liang

Abstract readCase ReportsReview
In one paragraph

Review in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yimei Lin *Department of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Jingyi Wu *Department of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Junmei WuDepartment of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Juanlan LiuDepartment of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Chao LiangDepartment of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China. superwm226@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery spasm (CAS) has been frequently documented during regional or general anesthesia. However, severe cardiac arrest induced by CAS as a result of anal-cardiac and vasovagal reflexes is relatively uncommon. CASE PRESENTATION: This report describes a patient with a history of CAS and percutaneous coronary angioplasty (PTCA) who experienced coronary artery spasm and subsequent cardiac arrest during anal anastomosis in a transabdominal perineal radical resection of rectal cancer (MILES procedure).

conclusionThis case study offers significant insights into the pathophysiology of cardiac arrest induced by surgical intervention in the anal region, which is densely innervated by the vagus nerve at the terminal portion of the rectum. This phenomenon may be associated with the anal cardiac reflex and vagus nerve reflexes. It is imperative to recognize the potential for catastrophic outcomes due to vagus nerve excitation during rectal end surgery, particularly in patients with a history of acute CAS.

Indexed as

Anal CanalCoronary VasospasmHeart ArrestIntraoperative ComplicationsProctectomyRectal NeoplasmsReflexHumansAnal-cardiac reflexCardiac arrestCoronary artery spasmMILES surgery

Identifiers

PMID40140877
PMCPMC11938595

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.