Evidence map›Paper›PMID 40140813›Full record

ArticleBMC oral health2025

The effects of the use of whitening mouthwash after home bleaching on the color stability and surface hardness of enamel.

Iklima Mehmethanoglu, Ipek Cubukcu, Neslihan Celik, Pinar Gul

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iklima MehmethanogluDepartment of Restorative Dentistry, Faculty of Dentistry, Atatürk University, Erzurum, TR-25240, Türkiye. gndgdiklima@gmail.com.
Ipek CubukcuDepartment of Restorative Dentistry, Faculty of Dentistry, Atatürk University, Erzurum, TR-25240, Türkiye.
Neslihan CelikDepartment of Restorative Dentistry, Faculty of Dentistry, Atatürk University, Erzurum, TR-25240, Türkiye.
Pinar GulDepartment of Restorative Dentistry, Faculty of Dentistry, Atatürk University, Erzurum, TR-25240, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effectiveness of whitening mouthwashes, both with and without hydrogen peroxide (HP), after at-home teeth whitening in preserving the achieved whiteness and assessing their impact on enamel surface hardness.

methodsOne hundred extracted human premolar teeth were divided into two groups, and home bleaching agents (Philips Zoom NiteWhite 22% Carbamide Peroxide, Ultradent Opalescence PF 16% Carbamide Peroxide) were applied to the groups. The teeth subjected to home bleaching were further divided into five subgroups, and each subgroup underwent a four-week cycle of application of a coloring agent and whitening mouthwash (Colgate Optic White (COW)(%2 HP), Rocs Black Edition (Rocs) (%1 HP), SPLAT Professional Bioactive gargle white Plus (SPLAT) (Ananas sativus fruit extract containing), Listerine Advanced White (Listerine) (Pyrophsphate containing), and distilled water (DW) (control)). Color and microhardness measurements were recorded at baseline, after home bleaching, and after treatment with whitening mouthwashes.

resultsCompared with those treated with Opalescence PF, the samples treated with Zoom achieved a significantly greater degree of whitening (p < 0.001). When the effects of postwhitening mouthwash were evaluated (ΔE

conclusionsHigher concentrations of carbamide peroxide provide faster and more effective whitening. Whitening mouthwash containing HP and pyrophosphate is effective in maintaining tooth whiteness after home bleaching; however, its impact on enamel microhardness depends on the formulation. Notably, only Listerine in the Opalescence PF group significantly increased surface hardness. Given the drawbacks of HP, pyrophosphate-based mouthwash may serve as a safer alternative.

Indexed as

Dental EnamelMouthwashesTooth BleachingTooth Bleaching AgentsCarbamide PeroxideColorDrug CombinationsHardnessHumansHydrogen PeroxidePeroxidesPhosphatesPlant ExtractsPolyvinylsSalicylatesSurface PropertiesCarbamide PeroxideDrug CombinationsHydrogen PeroxideListerineMouthwashesPeroxidesPhosphatesPlant ExtractsPolyvinylsSalicylatesTerpenestooth-bleaching agent, OpalescenceTooth Bleaching AgentsUreaColor stabilityEnamel surface hardnessHome bleachingHydrogen peroxidePineapple extractPyrophosphateWhitening mouthwash

Identifiers

PMID40140813
PMCPMC11948628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.