SynthesisBMC oral health2025
Efficacy of ozone therapy in dentistry with approach of healing, pain management, and therapeutic outcomes: a systematic review of clinical trials.
Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ozonated water as a preventive oral hygiene aid: a systematic review and meta-analysis of its role in reducing dental plaque.Evidence-based dentistry · 2026Pooled it
- Regenerative potential of Dental Pulp Stem Cells (DPSCs) in dental and periodontal tissue engineering: a systematic review of preclinical and clinical studies.BMC oral health · 2026Pooled it
- Effects of Intraoperative Ozone Application on Early Implant Stability: A Randomized Split-Mouth Clinical Trial.Journal of functional biomaterials · 2026Article
- Effect of Adjunctive Ozone Application Protocols on Dentin-Derived Growth Factor Release: An In Vitro Study.Journal of clinical medicine · 2026Article
- The use of ozone in oral health care: a narrative review of current evidence and clinical applications.Frontiers in oral health · 2026Review
- The Management of a Post-Extraction Gingival Lesion in a Paediatric Patient: A Case Report.Children (Basel, Switzerland) · 2025Article
- Advancing Bioprinting Technology Utilizing Portable Bioprinters: From Various Device Designs to Dental Applications.Annals of biomedical engineering · 2025Review
- Deep Learning-Based Evaluation of Postural Control Impairments Caused by Stroke Under Altered Sensory Conditions.Biomimetics (Basel, Switzerland) · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ozone therapy has emerged as a promising treatment modality in dentistry due to its antimicrobial and healing properties. This systematic review aimed to evaluate the recent clinical trials on ozone therapy in dentistry and its impact on therapeutic outcomes. A comprehensive literature search was conducted across multiple databases, including Web of Science, PubMed, and Scopus from January 2018 to December 2024, identifying studies that investigated the use of ozone in dental applications. The findings demonstrated that ozone therapy is effective in improving periodontal health, healing soft tissue after dental implant surgery, and reducing postoperative discomfort. The combination of scaling and root planing with gaseous ozone therapy showed superior periodontal response rates. The use of ozone during endodontics procedures resulted in reduced post-treatment pain, while ozonated materials showed promise in the management of dentinal hypersensitivity. However, it is not recommended in restorative dentistry due to potential adverse effects on dentinal bond strength. The findings of this systematic review supported the integration of ozone therapy into dentistry as an adjunctive therapy. More research is needed to elucidate its mechanisms, optimize application techniques, and evaluate long-term outcomes for patient safety and treatment effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.