Evidence map›Paper›PMID 40140780›Full record

Trial reportBMC oral health2025

Evaluation of the effect of manual lymphatic drainage method on edema, pain and trismus after impacted bilateral mandibular third molar surgery: a randomized clinical trial.

Murat Ulu, Nuri Ünal, Onur Şahin, Yasemin Kayalı

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06787027 (Evaluation of the Effect of Manual Lymphatic Drainage Method on Edema, Pain and Trismus After Impacted Bilateral Mandibular Third Molar Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06787027 nacompletednot on this map

Evaluation of the Effect of Manual Lymphatic Drainage Method on Edema, Pain and Trismus After Impacted Bilateral Mandibular Third Molar Surgery: a Randomized Clinical Trial

TypeinterventionalSponsorIzmir Katip Celebi UniversityRan2018 to 2018Enrolled46ConditionsImpacted Third Molar Tooth, Swelling/ Edema, Pain, TrismusArmsManual Lymphatic Drainage technique, Conventional Treatment group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Murat UluDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir, Turkey.ORCID http://orcid.org/0000-0002-3338-7198
Nuri ÜnalDepartment of Oral and Maxillofacial Surgery, Private Practice, İzmir, Turkey. dr.nuriunal@icloud.com.ORCID http://orcid.org/0000-0002-7017-0318
Onur ŞahinDeparment of Oral and Maxillofacial Surgery, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir, Turkey. onursahin43@hotmail.com.ORCID http://orcid.org/0000-0001-7816-1443
Yasemin KayalıPhysiotherapist, İzmir Atatürk Training and Research Hospital, Atatürk Eğitim ve Araştırma Hastanesi, Basın Sitesi, 35360 Karabağlar/İzmir, İzmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the effect of manual lymphatic drainage (MLD) on edema, pain and trismus after impacted mandibular third molar surgery. MATERIALS AND

methods46 patients with bilateral impacted mandibular third molar teeth were included in our study. The study was designed as a split-mouth, single-blinded, and controlled randomized clinical trial. Patients in the study group received MLD therapy, while the control group followed routine postoperative care including drug treatment. After extractions, the records were compared statistically and edema, pain and trismus parameters were evaluated on the 3rd and 7th days. The primary outcome variables was swelling and secondary outcome variables were pain and trismus. Swelling was evaluated using the 3dMD FACE SYSTEM (3dMD, Atlanta, GA). To assess pain, the Visual Analog Scale (VAS) was used and trismus was measured using with a digital caliper.

resultsThe present study was conducted on a total of 46 patients, aged between 18 and 26 years (18.7174 ± 1.50056), with bilaterally similar, symmetrical impacted mandibular third molars. The group consisted of 14 males (30.4%) and 32 females (69.6%). Postoperative edema, pain and trismus were found to be significantly lower in the MLD group compared to the control group (p < 0.05).

conclusionMLD technique is a useful method for reducing postoperative morbidity after impacted third molar extraction. The MLD technique is a simple method free from undesirable side effects and may be more effective than classical methods in reducing edema, pain and trismus after third molar extraction.

trial registrationThe trial was registered retrospectively on ClinicalTrials.gov (ID: NCT06787027, on 22/01/2025). Approved by Izmir Katip Celebi University Clinical Research Ethics Committee (Decision No: ID 19, on 15/02/2018).

Indexed as

DrainageEdemaMolar, ThirdPostoperative ComplicationsPostoperative PainTooth ExtractionTooth, ImpactedTrismusAdolescentAdultFemaleHumansMaleMandiblePain MeasurementSingle-Blind Method3dMDEdemaManual lymphatic drainageWisdom tooth

Identifiers

PMID40140780
PMCPMC11948945

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.