Evidence map›Paper›PMID 40140599›Full record

ArticleNature ecology & evolution2025

Pervasive gene flow despite strong and varied reproductive barriers in swordtails.

Stepfanie M Aguillon, Sophia K Haase Cox, Quinn K Langdon, Theresa R Gunn, John J Baczenas, Shreya M Banerjee, Alexandra E Donny, Benjamin M Moran, Paola Fascinetto-Zago, Carla Gutiérrez-Rodríguez and 4 more

Abstract read
In one paragraph

Article in Nature ecology & evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Sensitivity of genome-wide tests for mitonuclear genetic incompatibilities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Stepfanie M AguillonDepartment of Biology, Stanford University, Stanford, CA, USA. aguillon@ucla.edu.ORCID http://orcid.org/0000-0002-8254-6124
Sophia K Haase CoxDepartment of Biology, Stanford University, Stanford, CA, USA.
Quinn K LangdonDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-2141-3571
Theresa R GunnDepartment of Biology, Stanford University, Stanford, CA, USA.
John J BaczenasDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-6791-5470
Shreya M BanerjeeDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1210-2162
Alexandra E DonnyDepartment of Biology, Stanford University, Stanford, CA, USA.
Benjamin M MoranDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-5230-0863
Paola Fascinetto-ZagoCentro de Investigaciones Científicas de las Huastecas 'Aguazarca' A.C., Calnali, México.
Carla Gutiérrez-RodríguezRed de Biología Evolutiva, Instituto de Ecología A.C., Xalapa, México.ORCID http://orcid.org/0000-0002-7142-4164
Oscar Ríos-CárdenasRed de Biología Evolutiva, Instituto de Ecología A.C., Xalapa, México.ORCID http://orcid.org/0000-0003-3416-0814
Molly R MorrisDepartment of Biological Sciences, Ohio University, Athens, OH, USA.ORCID http://orcid.org/0000-0001-9962-2982
Daniel L PowellDepartment of Biology, Stanford University, Stanford, CA, USA.
Molly SchumerDepartment of Biology, Stanford University, Stanford, CA, USA. schumer@stanford.edu.ORCID http://orcid.org/0000-0002-2075-5668

Funding

The population genomics of hybridization: from genetic incompatibilities to genome evolutionR35GM133774 · NIGMS · STANFORD UNIVERSITY · PI Molly Schumer · 2019 to 2026
$3.3M
Alfred P. Sloan Foundation FellowshipFoundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) 1R35GM133774Howard Hughes Medical InstituteHoward Hughes Medical Institute (HHMI) Freeman-Hrabowski FellowshipHoward Hughes Medical Institute (HHMI) Hanna H. Gray FellowshipNational Science Foundation (NSF) IBN grant 9983561National Science Foundation (NSF) NSF Graduate Research Fellowship (2019273798)National Science Foundation (NSF) Postdoctoral Research Fellowship in Biology (2010950)NIGMS NIH HHS R35 GM133774Ohio University (OU) Research IncentiveStanford University (SU) Knight-Hennessy Scholars FellowshipStanford University (SU) Stanford Science FellowshipSU | Center for Computational, Evolutionary and Human Genomics, Stanford University (Center for Computational, Evolutionary and Human Genomics) Fellowship
6 · The paper itself

Abstract

The evolution of reproductive barriers leads to the formation of new species. However, recent research has demonstrated that hybridization has been pervasive across the tree of life even in the presence of strong barriers. Using swordtail fishes (genus Xiphophorus), an emerging model system, we document overlapping mechanisms that act as barriers to gene flow between Xiphophorus birchmanni and Xiphophorus cortezi by combining genomic sequencing from natural hybrid populations, experimental laboratory crosses, behavioural assays, sperm measures and developmental studies. We show that assortative mating plays a role in maintaining subpopulations with distinct ancestry within natural hybrid populations. Using F

Indexed as

CyprinodontiformesGene FlowHybridization, GeneticReproductive IsolationAnimalsFemaleMaleReproduction

Identifiers

PMID40140599
PMCPMC12066355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.