ArticleNature2025
Gene-modified pig-to-human liver xenotransplantation.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed.
- Combined organ xenotransplantation: from graft function to cross-species homeostasis.Life medicine · 2026Article
- Redefining post-xenotransplantation surveillance: leveraging metagenomic next-generation sequencing to discriminate true pathogen replication from microchimerism-induced false positives.Clinical transplantation and research · 2026Review
- The Asian perspective on xenotransplantation: bridging the organ gap through regional collaboration and tailored clinical protocols.Clinical transplantation and research · 2026Review
- Beyond immune rejection: integrative genetic engineering strategies for overcoming coagulopathy in xenotransplantation.Clinical transplantation and research · 2026Review
- Orthotopic liver xenotransplantation from gene-modified pig to decedent human.Nature biomedical engineering · 2026Article
- Genetically Modified and Gene-Edited Organisms-Objectives, Public Perception and Applications.Biology · 2026Review
- Genetically engineered porcine liver: a new era in transplantation.International journal of surgery (London, England) · 2026Article
- Bridging precision agriculture and human medicine through comparative genetics.Nature reviews. Genetics · 2026Review
- The International Chinese Young Scholars Alliance for the Study of the Liver: facilitating global collaboration.Nature reviews. Gastroenterology & hepatology · 2026Article
- Multiple genetic engineering of porcine red blood cells improves compatibility with human blood.iScience · 2026Article
- Research Progress and Critical Challenges of Bioartificial Kidneys in Renal Replacement Therapy for End-Stage Renal Disease.Biomolecules · 2026Review
- Article
- A Comparative Analysis of Pig-to-Rhesus Corneal Xenotransplantation with Various Immunosuppressive Regimens.Korean journal of ophthalmology : KJO · 2026Article
- Longitudinal multiomics profiling of extracorporeal cross-circulation with pig liver xenografts in human decedents.Nature medicine · 2026Article
- Multi-omics maps human-pig interactions in extracorporeal liver cross-circulation.Nature medicine · 2026Article
- Pig Matrix: a matched multiomics 3D regulatory genomics database for evolutionary and comparative analyses in pigs.Molecular biology and evolution · 2026Article
- Global profiling of the protein lactylome in porcine liver.BMC genomics · 2026Article
- Public awareness and acceptance of xenotransplantation in China: a cross-sectional survey.BMC medical ethics · 2026Article
- Engineering CAR T Cells for Hepatocellular Carcinoma Recurrence after Liver Transplantation.bioRxiv : the preprint server for biology · 2026Article
- Innovations in Liver Transplant.Gastroenterology & hepatology · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors.
Kai-Shan Tao *Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhao-Xu Yang *Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xuan Zhang *Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hong-Tao Zhang *Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Shu-Qiang YueDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yan-Ling YangDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.ORCID 0000-0001-8246-1756
Wen-Jie SongDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
De-Sheng WangDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zheng-Cai LiuDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hai-Min LiDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yong ChenDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Rui DingDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Shi-Ren SunDepartment of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Ming YuDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Ji-Peng LiDepartment of Experimental Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wei-Xun DuanDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhe WangDepartment of Pathology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jing-Wen WangDepartment of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jia-Yun LiuDepartment of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Min-Wen ZhengDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xi-Jing ZhangDepartment of Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wen YinDepartment of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wei-Jun QinDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dong-Mei BianDepartment of Surgery Operating Room, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Lin LiDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Min LiDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhi-Bin LinDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hao XuDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dan WeiDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hong ZhangDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Juan-Li DuanDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Deng-Ke PanChengdu Clonorgan Biotechnology Co. Ltd, Chengdu, China.
Hai-Long DongDepartment of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China. hldong6@hotmail.com.ORCID 0000-0001-8984-9067
Lin WangDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China. fierywang@163.com.ORCID 0000-0001-5586-3012
Ke-Feng DouDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China. doukef@fmmu.edu.cn.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The shortage of donors is a major challenge for transplantation; however, organs from genetically modified pigs can serve as ideal supplements
Indexed as
Animals, Genetically ModifiedHeterograftsLiverLiver TransplantationTransplantation, HeterologousAlanine TransaminaseAnimalsAspartate AminotransferasesB-LymphocytesBrain DeathC-Reactive ProteinFemaleHemodynamicsHumansMaleSwineAlanine TransaminaseAspartate AminotransferasesC-Reactive Protein
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.