Evidence map›Paper›PMID 40140567›Full record

ArticleNature2025

STING agonist-based ER-targeting molecules boost antigen cross-presentation.

Xiafeng Wang, Zhangping Huang, Lixiao Xing, Liru Shang, Juan Jiang, Caiguanxi Deng, Wei Yu, Lin Peng, Hao Yang, Xiaohong Zheng and 14 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Xiafeng Wang *Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0009-0001-1575-0010
Zhangping Huang *Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0009-0000-9705-5419
Lixiao Xing *Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University, Shanghai, China.ORCID 0000-0002-3027-1325
Liru Shang *Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0009-0008-3435-1200
Juan Jiang *Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0009-0006-6419-4109
Caiguanxi DengInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wei YuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Lin PengInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hao YangSchool of Life Sciences, Liaoning University, Shenyang, China.
Xiaohong ZhengInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xinmin LiuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Haolan YangInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yixin ChenInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yongyong LiInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jing LiuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xi XieState Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Material and Technology, School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-7406-8444
Wei XuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University, Shanghai, China.
Xiaojun XiaState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.ORCID 0000-0003-4444-7472
Zezhong LiuDepartment of Pharmacology and the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
Wanli LiuState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua-Peking Center for Life Sciences, Institute for Immunology, China Ministry of Education Key Laboratory of Protein Sciences, Beijing, China.ORCID 0000-0003-0395-2800
Shibo JiangKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University, Shanghai, China.ORCID 0000-0001-8283-7135
Yingyue ZengSchool of Life Sciences, Liaoning University, Shenyang, China. zengyingyue@lnu.edu.cn.ORCID 0000-0003-3808-4425
Lu LuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University, Shanghai, China. lul@fudan.edu.cn.ORCID 0000-0002-2255-0391
Ji WangInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. wangj683@mail.sysu.edu.cn.ORCID 0000-0002-8631-3264

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD8

Indexed as

Cross-PrimingEndoplasmic ReticulumMembrane ProteinsAnimalsAntigens, NeoplasmCD8-Positive T-LymphocytesCOVID-19COVID-19 VaccinesDendritic CellsEpitopesHumansMiceMice, Inbred C57BLSARS-CoV-2Spike Glycoprotein, CoronavirusSTING ProteinAntigens, NeoplasmCOVID-19 VaccinesEpitopesMembrane ProteinsSpike Glycoprotein, CoronavirusSTING1 protein, humanSting1 protein, mouseSTING Protein

Identifiers

PMID40140567
PMCPMC12043507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.