ArticleNature2025
A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome.
Erratum issuedAbstract read
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 64 papers.
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64citing papers in PubMed
–field-weighted citation impact
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
64 citing papers in PubMed.
- Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027Review
- Antibacterial efficacy and mechanism of the novel antimicrobial peptide lachnospirin-1 againstVirulence · 2026Article
- Review
- Diverse biosynthetic pathways in Arctic hydrothermal biofilms.Nature communications · 2026Article
- Chemoenzymatic Modification of Microcin J25 with Single-Residue Precision Provides New-to-Nature Lasso Peptides.JACS Au · 2026Article
- "Lariocidin and ribosome-targeting lasso peptides as emerging antimicrobial agents against multidrug-resistant bacteria".The Journal of antibiotics · 2026Review
- Synthesis of β-Thiolated Amino Acids: Investigation Toward the Total Chemical Synthesis of Lasso Peptide Microcin J25.Chembiochem : a European journal of chemical biology · 2026Article
- Fine-grained structural classification of biosynthetic gene cluster-encoded products.Bioinformatics (Oxford, England) · 2026Article
- Dual-Modal Phototherapeutic Nanoagents Eradicating Drug-Resistant Bacteria via Multi-Pathway of Membrane Disruption, Oxidative Damage, and Energy Metabolism Interference.Advanced healthcare materials · 2026Article
- A lab-on-a-silicon-chip platform for all-electrical antibiotic susceptibility tests with a sample-to-results time within 20 minutes.Science advances · 2026Article
- Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026Review
- Next-Generation Strategies to Encounter Antimicrobial Resistance (AMR): From Lariocidin to Gene Editing and Nanotechnology-Based Approaches.Molecules (Basel, Switzerland) · 2026Review
- Multiscale Modeling of the Bacterial Ribosome to Identify Potential Peptide Modulators and Their Allosteric Effects.Biochemistry · 2026Article
- Article
- Genetic and pharmacological inactivation of peptidoglycan remodeling increases antibiotic susceptibility of vancomycin-resistant Enterococcus faecium.Nature communications · 2026Article
- Current State of the Fight Against Antimicrobial Resistance: What Are the Different Strategies for Tomorrow?Antibiotics (Basel, Switzerland) · 2026Review
- Biosynthesis, Structure, and Antibiotic Properties of Gelatinamin A, a Triculamin-Like Lasso Peptide.Chembiochem : a European journal of chemical biology · 2026Article
- Arctic deep-sea hydrothermal microbiomes as a natural niche for novel antimicrobial peptides.BMC microbiology · 2026Article
- Benzoxaborole-modified azithromycins inhibit translation without inducingAntimicrobial agents and chemotherapy · 2026Article
- Structure, Biosynthesis, and Bioactivity of Nostolysamides.Biochemistry · 2026Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
- Update of
Authors and funding
18 authors.
Manoj Jangra *David Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-3423-7105
Dmitrii Y Travin *Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Elena V AleksandrovaDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Manpreet KaurDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-2506-0611
Lena DarwishDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.
Kalinka KotevaDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-6446-9567
Dorota KlepackiDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Wenliang WangDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.
Maya TiffanyDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.
Akosiererem SokariboDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.
Xuefei ChenDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.
Zixin DengState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Meifeng TaoState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Brian K CoombesDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-9883-1010
Nora Vázquez-LaslopDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0003-2256-693X
Yury S PolikanovDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA. yuryp@uic.edu.ORCID 0000-0002-5064-0327
Alexander S MankinDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA. shura@uic.edu.ORCID 0000-0002-3301-827X
Gerard D WrightDavid Braley Centre for Antibiotics Discovery, McMaster University, Hamilton, Ontario, Canada. wrightge@mcmaster.ca.ORCID 0000-0002-9129-7131
Funding
X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6MAdvancing ribosome-targeting antibacterial peptides with a unique mechanism of actionR01AI162961 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALEXANDER S MANKIN, Terry William Moore · 2022 to 2026
$3.3MUnraveling context specificity of translation by elucidating the mechanism of action of auxiliary translation factorsR35GM127134 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALEXANDER S MANKIN · 2018 to 2026
$3.2MMolecular mechanisms of action of ribosome-targeting antibiotics.R01GM132302 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI POLIKANOV, YURY · 2019 to 2022
$1.3MStructural basis for ribosome function and inhibition in bacteria.R35GM151957 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YURY POLIKANOV · 2024 to 2026
$1.2MNIAID NIH HHS R01 AI162961NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R01 GM132302NIGMS NIH HHS R35 GM127134NIGMS NIH HHS R35 GM151957
Abstract
Lasso peptides (biologically active molecules with a distinct structurally constrained knotted fold) are natural products that belong to the class of ribosomally synthesized and post-translationally modified peptides
Indexed as
Anti-Bacterial AgentsBacteriaPeptides, CyclicRibosomesAnimalsFemaleHumansMiceMicrobial Sensitivity TestsModels, MolecularPaenibacillusPeptidesProtein BiosynthesisRNA, Ribosomal, 16SRNA, Transfer, Amino AcylAnti-Bacterial AgentsPeptidesPeptides, CyclicRNA, Ribosomal, 16SRNA, Transfer, Amino Acyl
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.