Evidence map›Paper›PMID 40140463›Full record

ArticleScientific reports2025

Choroidal blood flow velocity and resistance in inferior posterior staphyloma using a novel superpixel technique in laser speckle flowgraphy.

Michiyuki Saito, Mizuho Mitamura, Koichi Yokoi, Kiriko Hirooka, Dong Zhenyu, Ryo Ando, Satoru Kase, Susumu Ishida

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PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Michiyuki SaitoDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan. s.michiyuki@med.hokudai.ac.jp.
Mizuho MitamuraDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Koichi YokoiDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Kiriko HirookaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Dong ZhenyuDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Ryo AndoDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Satoru KaseDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Susumu IshidaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined choroidal circulation in inferior posterior staphyloma (IPS) eyes using mean blur rate (MBR) and beat strength over MBR (BOM) from laser speckle flowgraphy. Eighteen eyes from 12 patients with treatment-naïve IPS were studied, including 9 eyes with subretinal fluid (SRF). The thinnest part of the choroid was identified via optical coherence tomography, and rubber bands were placed at bordering across the superior and inferior regions. MBR and BOM, indices of blood flow velocity and resistance, were measured and analyzed. The MBR ratio and the BOM ratio, both arbitrarily prepared markers to show greater circulatory characteristics of IPS in smaller values, were compared between eyes with and without SRF. On average, the inferior region had a lower MBR and a higher BOM than the superior region. Both the MBR and BOM ratios were smaller in IPS eyes with SRF than in IPS eyes without SRF (all: P < 0.05). The inferior region had lower choroidal blood flow velocity and higher resistance than the superior region in IPS. Greater circulatory characteristics of IPS were observed in eyes with SRF, suggesting that SRF was driven by the unbalanced distribution of choroidal blood flow.

Indexed as

ChoroidAdultAgedBlood Flow VelocityFemaleHumansLaser-Doppler FlowmetryMaleMiddle AgedRegional Blood FlowTomography, Optical CoherenceBeat strength over mean blur rateChoroidal blood flow resistanceInferior posterior staphylomaLaser speckle flowgraphySuperpixel technique

Identifiers

PMID40140463
PMCPMC11947203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.