ArticleActa parasitologica2025
Are There Atypical Leishmania Species Responsible for the Kala-Azar Persistence in Northeast Iran?
Article in Acta parasitologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Genetic Profiling of Leishmania Species Causing Human Visceral Leishmaniasis in Algeria.Acta parasitologica · 2026Article
- Viscerotropic Leishmaniasis in Iran: Current Insights and Future Directions: A Narrative Review.Iranian journal of parasitologyReview
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Authors and funding
6 authors.
Funding
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Abstract
porpuseHuman visceral leishmaniasis (HVL) is a severe form of leishmaniasis caused by protozoan parasites of the genus Leishmania.
methodsFrom 2013 to 2022, this study, molecular diagnosis was conducted on 50 pediatric bone marrow aspiration samples from northeast Iran, all of which had previously been confirmed to have visceral leishmaniasis. The ITS-rDNA gene and phylogenetic analysis were performed.
resultsThe results revealed that 49 samples tested positive for L. infantum species, whereas 1 sample was identified as L. major. All three L. infantum isolates showed similar haplotypes, whereas the L. major isolate exhibited nucleotide differences in the sequence analyzed.
conclusionIt could be concluded that visceral manifestations of cutaneous leishmaniasis in children living in endemic areas should be considered a contributing factor to the development of HVL. The present study provides a relatively comprehensive snapshot of unusual leishmania species status that could be responsible for HVL development.
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