ArticleESC heart failure2025
Severity of tricuspid regurgitation predicts risk of recurrence of atrial fibrillation after pulmonary vein isolation.
Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Clinical and imaging phenotypes.European heart journal supplements : journal of the European Society of Cardiology · 2026Article
- Interplay between medical and interventional therapies in valvular heart disease and heart failure: an expert opinion paper.ESC heart failure · 2026Review
- Right-heart reverse remodeling and heart failure symptom outcomes after catheter ablation in patients with persistent atrial fibrillation, heart failure, and functional tricuspid regurgitation.Frontiers in cardiovascular medicine · 2026Article
- Severity of tricuspid regurgitation predicts risk of recurrence of atrial fibrillation after pulmonary vein isolation.ESC heart failure · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTricuspid regurgitation (TR) results in right atrial remodelling, thus promoting the formation of a substrate for atrial fibrillation (AF). In turn, AF may cause TR by annulus dilatation. We investigated whether the presence of TR affects the efficacy of pulmonary vein isolation (PVI) for AF. METHODS AND
resultsIn patients undergoing PVI, we compared the severity of TR before and 6 months after the procedure. Moderate to severe TR was defined as advanced. Moreover, we investigated whether the severity of TR, at baseline and 6 months after PVI, predicted the recurrence of AF. Out of 320 patients, advanced TR at baseline was documented in 13.1%. Six months after PVI, the proportion of patients with advanced TR (13.1% to 7.2%; P < 0.001) decreased significantly. Compared with patients with post-interventional improvement of advanced TR, right atrial (RA) dilatation at baseline was more pronounced in patients without TR improvement (RA area 20.2 ± 4.4 vs. 26.6 ± 8.3 cm). The presence of advanced TR, particularly without improvement during the follow-up, increased the risk of AF recurrences compared with patients without advanced TR. Even after propensity-score matching, TR at baseline remained an independent risk predictor regarding recurrent AF [hazard ratio 2.2 (95% confidence interval, 1.1-4.9); P = 0.045]. Advanced MR was not associated with increased risk of AF.
conclusionsIn AF patients undergoing PVI, the presence of advanced TR, particularly without improvement 6 months after the procedure, was associated with an increased risk of AF recurrences.
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