Evidence map›Paper›PMID 40139695›Full record

ArticleJNCI cancer spectrum2025

Accelerometer-measured physical activity, sedentary behavior, and mortality among cancer survivors: the Women's Health Accelerometry Collaboration.

Eric T Hyde, Kelly R Evenson, Gretchen E Bandoli, Jingjing Zou, Noe C Crespo, Humberto Parada, Michael J LaMonte, Annie Green Howard, Steve Nguyen, Meghan B Skiba and 4 more

Abstract read
In one paragraph

Article in JNCI cancer spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eric T HydeHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-5896-0894
Kelly R EvensonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-3720-5830
Gretchen E BandoliHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0003-2167-8921
Jingjing ZouHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-4749-105X
Noe C CrespoDivision of Health Promotion and Behavioral Science, School of Public Health, San Diego State University, San Diego, CA, United States.
Humberto ParadaDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, United States.
Michael J LaMonteDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo-The State University of New York, Buffalo, NY, United States.ORCID 0000-0002-6669-5242
Annie Green HowardDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0003-0837-8166
Steve NguyenHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-5193-7042
Meghan B SkibaNursing and Health Science Division, College of Nursing, University of Arizona, Tucson, AZ, United States.ORCID 0000-0002-2244-5575
Tracy E CraneDivision of Medical Oncology, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, United States.ORCID 0000-0002-4288-134X
Marcia L StefanickStanford Prevention Research Center, Stanford University School of Medicine, Stanford University, Stanford, CA, United States.
I-Min LeeDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.ORCID 0000-0002-1083-6907
Andrea Z LaCroixHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-9532-976X

Funding

WOMEN'S HEALTH INITIATIVE - CLINICAL COORDINATING CENTER: TASK AREA B - LONG LIFE STUDY VISIT 2 LIMITED HOME VISIT75N92021D00001 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ANDERSON, GARNET L. · 2021 to 2025
$52.0M
Women's Health Study: Continued Follow-upR01CA047988 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 1991 to 2014
$28.2M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A275N92021D00002 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2021 to 2025
$6.9M
TALENT Shared Resources CoreU54CA285115 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard Matthew Cripps, MARIA ELENA MARTINEZ · 2023 to 2026
$6.6M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00004 · NHLBI · STANFORD UNIVERSITY · PI STEFANICK, MARCIA · 2021 to 2025
$6.5M
Research Education CoreU54CA285117 · NCI · SAN DIEGO STATE UNIVERSITY · PI Richard Matthew Cripps, MARIA ELENA MARTINEZ · 2023 to 2026
$6.2M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00003 · NHLBI · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA · 2021 to 2025
$5.0M
Objective Physical Activity and Cardiovascular Health in Women Aged 80 and OlderR01HL105065 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LACROIX, ANDREA Z. · 2011 to 2014
$5.0M
Women's Health Study: Continued Follow-UpR01HL080467 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E. · 2005 to 2010
$4.5M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI VITOLINS, MARA · 2021 to 2025
$4.2M
Women's Health Study: Infrastructure support for continued cohort follow-upU01CA182913 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 2019 to 2023
$4.0M
The Women's Health Study: Infrastructure Support for Continued Cohort Follow-upUM1CA182913 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 2014 to 2018
$4.0M
NCI NIH HHS K01 CA234317NCI NIH HHS R01 CA047988NCI NIH HHS R01 CA154647NCI NIH HHS R01 CA227122NCI NIH HHS U01 CA182913NCI NIH HHS U54 CA285115NCI NIH HHS U54 CA285117NCI NIH HHS UM1 CA182913NHLBI NIH HHS 75N92021D00001NHLBI NIH HHS 75N92021D00002NHLBI NIH HHS R01 HL043851NHLBI NIH HHS R01 HL080467NHLBI NIH HHS R01 HL105065NHLBI NIH HHS RC1 HL099355NHLBI NIH HHS T32HL07989NIAAA NIH HHS K01 AA027811NIA NIH HHS K99 AG082863NIA NIH HHS K99AG082863NIHNIH HHS 5R01CA227122NIH HHS CA154647NIH HHS K01 AA027811Office of Behavioral and Social Sciences ResearchOffice of Disease PreventionSan Diego State UniversityUniversity of California San DiegoWHI NIH HHS 75N92021D00003WHI NIH HHS 75N92021D00004WHI NIH HHS 75N92021D00005
6 · The paper itself

Abstract

backgroundData on prospective associations of accelerometer-measured physical activity, sedentary behavior, and mortality among cancer survivors are lacking. Our study examined accelerometer-measured daily physical activity (including light, moderate to vigorous, total, and steps), sedentary behavior (sitting time and mean bout duration), and mortality among cancer survivors in the Women's Health Accelerometry Collaboration.

methodsPostmenopausal women in the Collaboration who reported a cancer diagnosis at least 1 year prior to wearing an ActiGraph GT3X+ device on the hip for at least 4 of 7 days from 2011 to 2015 were included. Outcomes included all-cause, cancer-related, and cardiovascular disease (CVD)-related mortality. Covariate-adjusted Cox regression estimated hazard ratios (HRs) and 95% CIs for each physical activity and sedentary behavior measure in association with mortality.

resultsOverall, 2479 cancer survivors (mean [SD] age, 74.2 [6.7] years) were followed up for 8.3 years. For all-cause mortality (n = 594 cases), every 78.1 minutes per day in light physical activity, 96.5 minutes per day in total physical activity, 102.2 minutes per day in sitting time, and 4.8 minutes in a sitting bout duration had hazard ratios of 0.92 (95% CI = 0.84 to 1.01), 0.89 (95% CI = 0.80 to 0.98), 1.12 (95% CI = 1.02 to 1.24), and 1.04 (95% CI = 0.96 to 1.12), respectively. Linear associations for cancer mortality (n = 168) and CVD mortality (n = 109) were not statistically significant, except for steps (hazard ratio per 2469 steps/d = 0.66, 95% CI = 0.45 to 0.96) and sitting time (hazard ratio = 1.30, 95% CI = 1.02 to 1.67) for CVD mortality. Nonlinear associations showed benefits of moderate to vigorous physical activity (for all-cause and CVD mortality) and steps (all-cause mortality only) maximized at approximately 60 minutes per day and 5000-6000 steps per day, respectively.

conclusionsAmong postmenopausal cancer survivors, higher physical activity and lower sedentary behavior was associated with reduced hazards of all-cause and CVD mortality.

Indexed as

AccelerometryCancer SurvivorsExerciseNeoplasmsSedentary BehaviorAgedAged, 80 and overCardiovascular DiseasesFemaleHumansMiddle AgedPostmenopauseProportional Hazards ModelsProspective StudiesWomen's Health

Identifiers

PMID40139695
PMCPMC12062960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.