Evidence map›Paper›PMID 40139691›Full record

ArticleLife science alliance2025

Molecular mechanism of bacteriophage contraction structure of an S-layer-penetrating bacteriophage.

Jason S Wilson, Louis-Charles Fortier, Robert P Fagan, Per A Bullough

Abstract read
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Journal of virology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason S WilsonMolecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, UK j.s.wilson@sheffield.ac.uk.ORCID 0000-0002-6967-0809
Louis-Charles FortierDepartment of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.ORCID 0000-0003-1950-763X
Robert P FaganMolecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, UK r.fagan@sheffield.ac.uk.ORCID 0000-0002-8704-4828
Per A BulloughMolecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, UK p.bullough@sheffield.ac.uk.ORCID 0000-0001-8147-1127

Funding

Biotechnology and Biological Sciences Research Council BB/P02002X/1Wellcome TrustWellcome Trust, Medical Research Council, and Biotechnology and Biological Sciences Research Council PROPOSAL EM19832
6 · The paper itself

Abstract

The molecular details of phage tail contraction and bacterial cell envelope penetration remain poorly understood and are completely unknown for phages infecting bacteria enveloped by proteinaceous S-layers. Here, we reveal the extended and contracted atomic structures of an intact contractile-tailed phage (φCD508) that binds to and penetrates the protective S-layer of the Gram-positive human pathogen

Indexed as

BacteriophagesBacteriophage T4Cell WallClostridioides difficileModels, MolecularViral Tail ProteinsViral Tail Proteins

Identifiers

PMID40139691
PMCPMC11948020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.