Evidence map›Paper›PMID 40138533›Full record

ArticleCritical care explorations2025

Outcome Predictions at Two Time Points among Surrogates and Physicians of Mechanically Ventilated Patients.

Benjamin Dufour, Hannah M Duehren, Ashley Eaton England, Kevin Keuper, Thomas V Quinn, Raj C Shah, Quyen M Diep, James Gerhart, Jared A Greenberg

Abstract read
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Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benjamin DufourRush Medical College, Chicago, IL.
Hannah M DuehrenDepartment of Internal Medicine, Rush University Medical Center, Chicago, IL.
Ashley Eaton EnglandDepartment of Psychology, Central Michigan University, Mt. Pleasant, MI.
Kevin KeuperDepartment of Internal Medicine, Rush University Medical Center, Chicago, IL.
Thomas V QuinnDivision of Pulmonary and Critical Care Medicine, Northwestern Medicine Palos Hospital, Palos Heights, IL.
Raj C ShahDepartment of Family and Preventive Medicine, Rush University Medical Center, Chicago, IL.
Quyen M DiepBioinformatics and Biostatistics Core, Rush University Medical Center, Chicago, IL.
James GerhartDepartment of Psychology, Ohio University, Athens, OH.
Jared A GreenbergDivision of Pulmonary and Critical Care, Department of Internal Medicine, Rush University Medical Center, Chicago, IL.ORCID 0000-0002-3446-2903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe decisions surrogates and physicians make for incapacitated critically ill patients depend in part on their expectations for patient recovery. We sought to determine whether the accuracy of surrogate and physician outcome predictions made during the ICU stay improves over time.

designSurvey study.

settingAcademic Medical Center. SUBJECTS: Surrogates and physicians of 100 mechanically ventilated patients from March 2018 to April 2019.

interventionsAt the end of the first week of mechanical ventilation and 1 week later, participants indicated on visual analog scales (0-100%) expectations that the patient would require mechanical ventilation in 1 month, require artificial nutrition in 1 month, be alive in 3 months, and be living at home in 3 months. Patient status was determined at 1 and 3 months. MEASUREMENTS AND MAIN

resultsArea under the receiver operating characteristic curves (AUROCs) were determined for each outcome, at each time point. Patients who died within the first month were considered to require mechanical ventilation and artificial nutrition in the primary analysis. AUROCs for initial surrogate predictions were 0.61 (95% CI, 0.50-0.72) for mechanical ventilation, 0.67 (95% CI, 0.56-0.78) for artificial nutrition, 0.66 (95% CI, 0.55-0.7) for survival, and 0.61 (95% CI, 0.50-0.73) for living at home. AUROCs for initial physician predictions were 0.60 (95% CI, 0.49-0.71) for mechanical ventilation, 0.72 (95% CI, 0.61-0.0.83) for artificial nutrition, 0.69 (95% CI, 0.59-0.80) for survival, and 0.76 (95% CI, 0.66-0.85) for living at home. Average expectations among surrogates and physicians were highly stable over time; adjustments made to expectations did not result in more accurate predictions for the measured outcomes (p > 0.05).

conclusionsAmong surrogates and physicians of patients who were mechanically ventilated for 1 week, outcome predictions were better than would be expected by chance and not significantly improved 1 week later.

Indexed as

Critical IllnessPhysiciansRespiration, ArtificialAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedROC CurveSurveys and QuestionnairesTime Factors

Identifiers

PMID40138533
PMCPMC11949294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.