Article in The Plant cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Liwei RongThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0006-3727-4621
Junhang AnThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0001-5077-3691
Xinyue ChenThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0002-5111-289X
Chao WangThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0002-0534-8984
Jianghao WuThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0009-6869-3206
Peng WangSchool of Biological Sciences, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-8420-5326
Yongxing ZhengThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0007-8065-212X
Xin WangHenan-Macquarie Uni Joint Centre for Biomedical Innovation, Academy for Advanced Interdisciplinary Studies, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0004-2370-0779
Xin ChaiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0002-0763-9574
Wei LiThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0002-1400-8356
Zhubing HuThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0002-5394-9864
Dandan LuThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0001-7700-7217
Guangyu E ChenState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0001-8457-819X
Min OuyangNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-2249-3470
Bernhard GrimmInstitute of Biology/Plant Physiology, Humboldt-Universität zu Berlin, Berlin 10115, Germany.ORCID 0000-0002-9730-1074
Lixin ZhangThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0006-5479-6691
Xiumei XuThe Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Key Laboratory of Synthetic Biology and Biomanufacturing, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0003-3515-1864
Funding
111 Project (#D16014Central Plains Scholar 234000510005German Research FoundationHainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City 2021JJLH0044National Key Research and Development Program 2022YFF1001700National Natural Science Foundation of China 32170258Natural Science Foundation of Henan Province 222300420026Program for Innovative Research Team (in Science and Technology) in University of Henan Province 25IRTSTHN025
6 · The paper itself
Abstract
Chlorophyll biosynthesis must be tightly coupled to light-harvesting chlorophyll a/b-binding protein (LHCP) biogenesis, as free chlorophyll and its precursors are phototoxic. However, precisely how these 2 processes are coordinated in Arabidopsis (Arabidopsis thaliana) remains elusive. Our previous studies demonstrated the role of LHCP TRANSLOCATION DEFECT (LTD) in delivering LHCPs to the chloroplast via the signal recognition particle-dependent pathway. Here, we show that LTD interacts with and stabilizes the chlorophyll biosynthesis enzymes Mg-protoporphyrin methyltransferase and Mg-protoporphyrin monomethylester (MgPME) cyclase, maintaining their activity. We also demonstrate the direct binding of LTD to MgPME, and through crystal structure analysis, we show that the groove of the LTD dimer is critical for MgPME binding. Thus, we propose that LTD transfers MgPME from Mg-protoporphyrin methyltransferase to the MgPME cyclase. These results elucidate a role for LTD in synchronizing chlorophyll biosynthesis with LHCP transport to ensure the correct insertion of chlorophylls into LHCPs.
Indexed as
ArabidopsisArabidopsis ProteinsChlorophyllLight-Harvesting Protein ComplexesChloroplastsMethyltransferasesProtein TransportArabidopsis ProteinsChlorophyllLight-Harvesting Protein Complexesmagnesium-protoporphyrin methyltransferaseMethyltransferases
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
LTD coordinates chlorophyll biosynthesis and LIGHT-HARVESTING CHLOROPHYLL A/B-BINDING PROTEIN transport. · full record | OpenQuestion