ArticlePloS one2025
Deep phenotyping to understand hearing and hearing disorders: Protocol for a feasibility study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association between lifetime noise exposure and audiometric thresholds using the noise exposure structured interview.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Globally, hearing loss affects around 1.5 billion people, while tinnitus is estimated to impact around 740 million. More research is urgently needed to address the challenges presented by hearing loss, tinnitus, and other hearing-related conditions. Our plans for a Nottingham Hearing BioResource, providing research-willing volunteers and comprehensive tests of hearing and ear health repeated over time, has the potential to accelerate the field. The protocol described here is a feasibility study for this BioResource, specifically addressing questions of recruitment from the general population (i.e., outside of clinical audiology services or pathways). Participants with or without known hearing problems will be recruited for data collection. This study will quantify how feasible it will be to recruit and retain a large sample of the general population, and will suggest the demographic, and hearing condition status, distributions we could achieve for the BioResource. Data collection will involve a health and lifestyle questionnaire; cognitive assessment; five questionnaires about hearing loss, tinnitus, and hyperacusis; an estimation of lifetime noise exposure; a suite of in-depth audiological tests; and taking a hair sample. The same measurements will be taken on two separate occasions in person, and a third set of overlapping measurements will be taken remotely. Repeating the data collection will allow us to evaluate participant retention rates and establish the reliability of the measures. The findings from this feasibility study will allow us to assess which channels work well to recruit a diverse pool of participants, which, when used in conjunction with recruitment from clinic, will provide the basis for a recruitment strategy for our BioResource. In addition, we will gain useful insight into whether specific tests or questionnaires used in the feasibility study are suitable for inclusion in a deep phenotyping protocol.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.