ArticleInternational journal of implant dentistry2025
Histological study of the effect of different hydration times of bone allograft and xenograft particles on the rate of bone formation in critical size defects in the rat calvarium.
Article in International journal of implant dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThe aim of this study was to investigate the effect of different bone graft hydration times on bone regeneration.
methodsFive-mm defects were created on either side of the sagittal plane in the calvaria of 40 rats. In each rat, the right and left defects were filled with allograft (Cenobone
resultsThere was no significant difference regarding the mean of new bone, remaining graft, and connective tissue between the xenograft samples in different hydration groups. In the allograft groups, the mean new bone formation of the no-hydration and 2-minute saline-hydrated groups was significantly lower than 30-minute saline-hydrated and blood hydrated groups (P = 0.03 and P = 0.03, respectively). Regarding the variable of the remaining graft particles, the results were almost similar.
conclusionsThe results of this study showed that, the method of bone graft hydration before it is used in treating bone lesions affects osteogenesis. Especially in the case of allograft, rehydration before usage at least for 10 min is recommended.
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